1421914-69-3Relevant academic research and scientific papers
Site-selective mono-oxidative addition of active zinc into carbon-bromine bond of dibrominated-thiophenes: Preparation of thienylzinc reagents and their applications
Jung, Hye-Soo,Cho, Hyun-Hee,Kim, Seung-Hoi
, p. 960 - 964 (2013/02/25)
A facile protocol for the preparation of 3-bromo-2-thienylzinc bromide A and 5-bromo-2-thienylzinc bromide B has been developed. It has been successfully accomplished by a site-selective oxidative addition of active zinc into a chemically pseudo-equivalent or equivalent carbon-bromine bond, respectively. The subsequent cross-coupling reactions of the organozincs were also successfully carried out under mild conditions providing the corresponding products in moderate to high yields.
