1421917-35-2

Upstream product

• 155377-19-8 ethyl 3-trifluoromethyl-1H-pyrazole-4-carboxylate 
• 571-55-1 ethyl 2-(ethoxymethylidene)-4,4,4-trifluoro-3-oxobutanoate 
• 142818-01-7 1-phenyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid 
• 741717-63-5 ethyl 1-phenyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylate 
• 14432-12-3 4-Amino-2-chloropyridine 
• 1003579-29-0 1-phenyl-3-(trifluoromethyl)-1H-pyrazole-4-carbonyl chloride 

Relevant academic research and scientific papers

Synthesis and antifungal activity of n-(substituted pyridinyl)- 1-methyl(phenyl)-3-(trifluoromethyl)-1h-pyrazole-4- carboxamide derivatives

A series of N-(substituted pyridinyl)-1-methyl(phenyl)-3-trifluoromethyl- 1Hpyrazole- 4-carboxamide derivatives were synthesized. All target compounds were characterized by spectral data (1H-NMR, 13C-NMR, IR, MS) and elemental analysis and were bioassayed in vitro against three kinds of phytopathogenic fungi (Gibberella zeae, Fusarium oxysporum, Cytospora mandshurica). The results showed that some of the synthesized N-(substituted pyridinyl)-1-methyl-3- trifluoromethyl-1H-pyrazole-4-carboxamides exhibited moderate antifungal activities, among which compounds 6a, 6b and 6c displayed more than 50% inhibition activities against G. zeae at 100 μg/mL, which was better than that of the commercial fungicides carboxin and boscalid.