14221-77-3Relevant academic research and scientific papers
NOVEL AROMATIC COMPOUND AND USE THEREOF
-
Paragraph 0608-0610, (2016/08/17)
Provided is a compound showing a bone formation promoting action (and/or bone resorption suppressive action). A compound of the formula (I) or a pharmacologically acceptable salt: [wherein each substituent is as defined in the DESCRIPTION], has low toxicity, shows good pharmacokinetics, has an action to promote bone formation, and is useful for the prophylaxis or To treatment of metabolic bone diseases (osteoporosis, fibrous osteitis (hyperparathyroidism), osteomalacia, Paget's disease that influences the systemic bone metabolism parameter etc.) associated with a decrease in the bone formation ability as compared to the bone resorption capacity.
SPIROKETONE ACETYL-COA CARBOXYLASE INHIBITORS
-
, (2008/12/06)
The invention provides compounds of Formula (1) or a pharmaceutically acceptable salt of said compound, wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating mammals suffering from the condition of being overweight.
Benzopyrones. Part 22. Synthesis of New 4-Oxochromene Polycarboxylic Acids
Ellis, Gwynn P.,Hudson, Henrietta V.
, p. 3830 - 3860 (2007/10/02)
The synthesis of the following chromone dicarboxylic acids is described: 4-oxochromene-2,7-dicarboxylic acid, 6-methyl-4-oxochromene-2,8-dicarboxylic acid, 7-hydroxy-4-oxochromene-2,8-dicarboxylic acid, and 4-oxochromene-3,6-dicarboxylic acid. 4-Oxochromene-2,3-dicarboxylic acid 2-ethyl ester has been synthesized as well as 4-oxochromene-2,6,8-tricarboxylic acid.Some derivatives of these acids are described and the relative stability of carboxy groups attached to the chromen-4-one ring system is discussed.
