1422207-87-1Relevant articles and documents
Novel in vivo active anti-malarials based on a hydroxy-ethyl-amine scaffold
Ciana, Claire-Lise,Siegrist, Romain,Aissaoui, Hamed,Marx, Leo,Racine, Sophie,Meyer, Solange,Binkert, Christoph,De Kanter, Ruben,Fischli, Christoph,Wittlin, Sergio,Boss, Christoph
, p. 658 - 662 (2013/03/14)
A novel series of anti-malarials, based on a hydroxy-ethyl-amine scaffold, initially identified as peptidomimetic protease inhibitors is described. Combination of the hydroxy-ethyl-amine anti-malarial phramacophore with the known Mannich base pharmacophor