1422255-68-2

Upstream product

• 1422255-64-8 (4R,5R)-benzyl 5-fluoro-4-hydroxyhexanoate 
• 1422255-63-7 (R)-5-((R)-1-fluoroethyl)dihydrofuran-2(3H)-one 
• 54656-51-8 (R)-5-((S)-1-hydroxyethyl)dihydrofuran-2(3H)-one 
• 876152-40-8 (S)-1-((R)-5-oxotetrahydrofuran-2-yl)ethyl 4-nitrobenzoate 
• 1422255-56-8 (4S,5R)-4-ammonio-5-fluorohexanoate 
• 20445-33-4 (R)-methoxytrifluoromethylphenylacetyl chloride 
• 130609-14-2 (R)-5-((R)-1-hydroxyethyl)dihydrofuran-2(3H)-one 
• 34495-74-4 Ethyl 4-hexenoate 

Relevant academic research and scientific papers

Probing the steric requirements of the γ-aminobutyric acid aminotransferase active site with fluorinated analogues of vigabatrin

We have synthesized three analogues of 4-amino-5-fluorohexanoic acids as potential inactivators of γ-aminobutyric acid aminotransferase (GABA-AT), which were designed to combine the potency of their shorter chain analogue, 4-amino-5-fluoropentanoic acid (