876152-40-8Relevant academic research and scientific papers
INACTIVATORS OF TOXOPLASMA GONDII ORNITHINE AMINOTRANSFERASE FOR TREATING TOXOPLASMOSIS AND MALARIA
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Paragraph 0104; 0130, (2018/04/20)
Disclosed are methods, compounds, and compositions for treating infection by an Apicomplexan parasite that include administering a compound that selectively inactivates ornithine aminotransferase of the Apicomplexan parasite. Specifically, the methods, co
Probing the steric requirements of the γ-aminobutyric acid aminotransferase active site with fluorinated analogues of vigabatrin
Juncosa Jr., Jose I.,Groves, Andrew P.,Xia, Guoyao,Silverman, Richard B.
, p. 903 - 911 (2013/03/13)
We have synthesized three analogues of 4-amino-5-fluorohexanoic acids as potential inactivators of γ-aminobutyric acid aminotransferase (GABA-AT), which were designed to combine the potency of their shorter chain analogue, 4-amino-5-fluoropentanoic acid (
Synthesis of the C14-C28 fragment of tetronasin
Bourque, Elyse,Kocienski, Philip J.,Stocks, Michael,Yuen, Josephine
, p. 3219 - 3224 (2007/10/03)
A synthesis of the C14-C28 fragment of Tetronasin features an S E2 reaction between a cationic η3-allylmolybdenum complex and and an α-metallated tetrahydrofuran. Georg Thieme Verlag Stuttgart.
