1422264-35-4

Basic information

• Product Name: C₁₇H₁₈ClIN₄O₃
• Synonyms: C₁₇H₁₈ClIN₄O₃
• CAS NO: 1422264-35-4
• Molecular Weight: 488.712
• Mol File: 1422264-35-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₈ClIN₄O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₈ClIN₄O₃(1422264-35-4)
• EPA Substance Registry System: C₁₇H₁₈ClIN₄O₃(1422264-35-4)

Safety Data

• Hazardous Substances Data: 1422264-35-4(Hazardous Substances Data)

Upstream product

• 471-47-6 oxamic acid 
• 1429194-59-1 C₁₅H₁₇ClIN₃O 
• 1049809-74-6 3-(4-Chloro-3-iodo-phenyl)-1-(3-hydroxy-propyl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine-5-carboxylic acid tert-butyl ester 
• 1049809-51-9 3-(4-chloro-3-iodo-phenyl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]-pyridine-5-carboxylic acid tert-butyl ester 

Downstream Products

• 1049814-41-6 C₃₇H₄₀Cl₂N₆O 
• 1049814-29-0 2-[3-(4-Chloro-3-{[4-({[(4-chlorophenyl)methyl]amino]methyl)phenyl]ethynyl]phenyl)-1-{3-[4-(trifluoromethyl)piperidin-1-yl]propyl}-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl]-2-oxoacetamide 
• 1049813-84-4 3-(4-Chloro-3-{[4-({[(4-chlorophenyl)methyl]amino]methyl)phenyl]ethynyl]phenyl)-1-[3-(4-phenylpiperazin-1-yl)propyl]-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide 
• 1049817-65-3 C₃₆H₃₈Cl₂N₆OS 
• 1049813-33-3 3-(4-chloro-3-((4-((((4-chlorophenyl)methyl)amino)methyl)phenyl)ethynyl)phenyl)-1-(3-((3S)-3-methylmorpholin-4-yl)propyl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide 
• 1422264-37-6 C₃₈H₃₉Cl₂N₅O₅ 

Relevant articles and documents

Pyrazole-based arylalkyne Cathepsin S inhibitors. Part III: Modification of P4 region

Novel classes of tetrahydropyrido-pyrazole thioether amines and arylalkynes that display potency against human Cathepsin S have been previously reported. Here, key pharmacophoric elements of these two classes are merged, and SAR investigations of the P4 region are described, in conjunction with re-optimization of the P5 and P1/P1′/P3 regions. Identification of meta-substituted arylalkynes with good potency and improved solubility is described.