142259-49-2Relevant academic research and scientific papers
Click-chemistry approach to isoxazole-containing α-CF 3-substituted α-aminocarboxylates and α-aminophosphonates
Vorobyeva, Daria V.,Karimova, Natalya M.,Odinets, Irina L.,Roeschenthaler, Gerd-Volker,Osipov, Sergey N.
experimental part, p. 7335 - 7342 (2011/11/30)
A convenient strategy for the synthesis of isoxazole-containing α-CF3-substituted α-aminocarboxylates and α-aminophosphonates have been developed. The method is based on copper-catalyzed 1,3-dipolar cycloaddition of different aromatic nitrile o
Synthesis of 2-Heteroaryl-Substituted 3,3,3-Trifluoroalanine and 3,3,3-Trifluorolactic Acid Derivatives
Sewald, Norbert,Burger, Klaus
, p. 947 - 952 (2007/10/02)
Trifluoromethyl-substituted alkynyl α-amino acid as well as alkynyl α-hydroxy acid esters and 1,3-dipoles (nitrile oxides, diazoalkanes, phenyl azide) react regioselectively to give α-trifluoromethyl-substituted heterocyclic α-amino and α-hydroxy acid der
