128970-29-6

Basic information

• Product Name: 3-Butynoic acid, 2-[[(phenylmethoxy)carbonyl]amino]-2-(trifluoromethyl)-, methyl ester
• CAS NO: 128970-29-6
• Molecular Formula: C14H12F3NO4
• Molecular Weight: 315.249
• Mol File: 128970-29-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-Butynoic acid, 2-[[(phenylmethoxy)carbonyl]amino]-2-(trifluoromethyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Butynoic acid, 2-[[(phenylmethoxy)carbonyl]amino]-2-(trifluoromethyl)-, methyl ester(128970-29-6)
• EPA Substance Registry System: 3-Butynoic acid, 2-[[(phenylmethoxy)carbonyl]amino]-2-(trifluoromethyl)-, methyl ester(128970-29-6)

Safety Data

• Hazardous Substances Data: 128970-29-6(Hazardous Substances Data)

Upstream product

• 1066-26-8 sodium acetylide 
• 276862-98-7 2-[(E)-Benzyloxycarbonylimino]-3,3,3-trifluoro-propionic acid methyl ester 
• 128970-26-3 2-benzyloxycarbonylimino-3,3,3-trifluoropropionic acid methyl ester 

Downstream Products

• 1027761-26-7 C₁₇H₁₄F₃NO₄ 
• 1222169-95-0 methyl 4-(2-aminophenyl)-2-[(benzyloxycarbonyl)amino]-2-(trifluoromethyl)but-3-ynoate 
• 1222169-94-9 methyl 2-[(benzyloxycarbonyl)amino]-4-(2-nitrophenyl)-2-(trifluoromethyl)but-3-ynoate 
• 142259-55-0 3,3,3-Trifluor-2-<3-(4-fluorphenyl)isoxazol-5-yl>alanin-methylester 
• 142259-59-4 N-Benzyloxycarbonyl-3,3,3-trifluor-2-(1-phenyl-1,2,3-triazol-4-yl)alanin-methylester 
• 142259-47-0 methyl N-[(benzyloxy)carbonyl]-3,3,3-trifluoro-2-(3-phenylisoxazol-5-yl)alaninate 
• 142259-53-8 N-Benzyloxycarbonyl-2,2,2-trifluor-1-<3-(4-fluorphenyl)isoxazol-5-yl>ethylamin 
• 142259-49-2 N-Benzyloxycarbonyl-3,3,3-trifluor-2-<3-(4-fluorphenyl)isoxazol-5-yl>alanin-methylester 
• 142259-50-5 N-Benzyloxycarbonyl-2-(3-bromisoxazol-5-yl)-3,3,3-trifluoralanin-methylester 
• 142259-52-7 N-Benzyloxycarbonyl-1-<3-(4-chlorophenyl)isoxazol-5-yl>-2,2,2-trifluoroethylamin 
• 142259-48-1 N-Benzyloxycarbonyl-2-<3-(4-chlorphenyl)isoxazol-5-yl>-3,3,3-trifluoralanin-methylester 
• 142259-58-3 N-Benzyloxycarbonyl-2-(5-ethoxycarbonyl-3-pyrazolyl)-3,3,3-trifluoralanin-methylester 
• 1345465-49-7 methyl N-[(benzyloxy)carbonyl]-3,3,3-trifluoro-2-[3-(4-methoxyphenyl)isoxazol-5-yl]alaninate 
• 1345465-63-5 methyl N-[(benzyloxy)carbonyl]-3,3,3-trifluoro-2-[3-(4-nitrophenyl)isoxazol-5-yl]alaninate 

Relevant articles and documents

Synthesis of α-Alkynyl-β,β,β-trifluoroalanine Derivatives by Sonogashira Cross-Coupling Reaction

An efficient route to new a-CF3-a-amino acid derivatives bearing an arylalkynyl moiety at the a-carbon atom has been developed. The method is based on palladium-catalyzed cross-coupling of the corresponding a-propargyl (ethynyl) a- amino esters

α-Trifluormethyl Substituted Amino Acids with Alkyne Functions in the Side Chain

Starting from trifluoro pyruvates and terminal alkynes a simple preparative procedure for synthesis of α-trifluoromethyl substituted acetylenic α-amino acids and α,ω-diamino dicarboxylic acids is described.The triple bond in the side chain can be function