128970-29-6Relevant academic research and scientific papers
Synthesis of α-Alkynyl-β,β,β-trifluoroalanine Derivatives by Sonogashira Cross-Coupling Reaction
Shchetnikov, Grigorii T.,Zotova, Maria A.,Bruneau, Christian,Dixneuf, Pierre H.,Osipov, Sergey N.
experimental part, p. 1587 - 1592 (2010/06/15)
An efficient route to new a-CF3-a-amino acid derivatives bearing an arylalkynyl moiety at the a-carbon atom has been developed. The method is based on palladium-catalyzed cross-coupling of the corresponding a-propargyl (ethynyl) a- amino esters
Ruthenium-catalyzed cyclotrimerization of 1,6- and 1,7-azadiynes: New access to fluorinated bicyclic amino acids
Shchetnikov, Grigorii T.,Osipov, Sergey N.,Bruneau, Christian,Dixneuf, Pierre H.
, p. 578 - 582 (2008/12/22)
An efficient access to a variety of trifluoromethyl-substituted cyclic α-amino acid derivatives based on ruthenium-catalyzed cyclotrimerization of appropriate 1,6- and 1,7-diynes with terminal and internal alkynes has been developed. Georg Thieme Verlag S
α-Trifluormethyl Substituted Amino Acids with Alkyne Functions in the Side Chain
Burger, Klaus,Sewald, Norbert
, p. 115 - 118 (2007/10/02)
Starting from trifluoro pyruvates and terminal alkynes a simple preparative procedure for synthesis of α-trifluoromethyl substituted acetylenic α-amino acids and α,ω-diamino dicarboxylic acids is described.The triple bond in the side chain can be function
