1422667-73-9Relevant academic research and scientific papers
The cyclopropyliminium rearrangement of cyclopropylthiazoles
Tomilov, Yury V.,Salikov, Rinat F.,Platonov, Dmitry N.,Lipilin, Dmitry L.,Frumkin, Aleksandr E.
, p. 22 - 23 (2013)
2-Cyclopropylthiazole hydrobromides undergo iminocyclopropane-pyrroline rearrangement in a melt to give the corresponding fused heterocycles, viz. 6,7-dihydro-5H-pyrrolo[2,1-b]thiazol-4-ium bromides. 2-Alkyl- and 2-aryl-4-cyclopropylthiazoles transform into analogous fused heterocycles as hydroiodides and noticeably longer.
One-step synthesis of methanesulfonyloxymethyl ketones via gold-catalyzed oxidation of terminal alkynes: A combination of ligand and counter anion enables high efficiency and a one-pot synthesis of 2,4-disubstituted thiazoles
Wu, Gongde,Zheng, Renhua,Nelson, Jonathan,Zhang, Liming
supporting information, p. 1229 - 1234 (2014/05/06)
By using Mor-DalPhos as the P,N-bidentate ligand and mesylate as the counter ion, the resulting gold(I) complex catalyzes efficient oxidative transformations of various terminal alkynes into synthetically versatile methanesulfonyloxymethyl ketones. The mild reaction conditions and high efficiency permit the one-pot synthesis of a range of valuable 2,4-disubstituted thiazoles by subjecting the resulting reaction mixture to a further condensation with thioamides under mild conditions.
