142272-85-3

Upstream product

• 36678-63-4 ethoxyethynylmagnesium bromide 
• 98-86-2 acetophenone 
• 42345-82-4 (E)-1,2-dichloro-1-ethoxy-ethene 
• 927-80-0 1-ethoxyacetylene 

Downstream Products

• 90054-63-0 3-Hydroxy-2-oxo-3-phenylbutyric acid ethyl ester 
• 1398402-06-6 (Z)-1-(furan-2-yl)-3-phenylbut-2-en-1-one 
• 1398402-01-1 (E)-1-(furan-2-yl)-3-phenylbut-2-en-1-one 
• 1398401-95-0 (Z)-1-(1-methyl-1H-pyrrol-2-yl)-3-phenylbut-2-en-1-one 
• 1398401-88-1 (E)-1-(1-methyl-1H-pyrrol-2-yl)-3-phenylbut-2-en-1-one 
• 1398401-83-6 (Z)-1-(1H-indol-3-yl)-3-phenylbut-2-en-1-one 
• 1398401-74-5 (Z)-1-(2,4-dimethoxyphenyl)-3-phenylbut-2-en-1-one 
• 1398401-69-8 (E)-1-(2,4-dimethoxyphenyl)-3-phenylbut-2-en-1-one 
• 1196-67-4 3-phenyl-2-butenal 
• 1504-72-9 ethyl 3-phenylbut-2-enoate 

Relevant academic research and scientific papers

Synthesis of β-substituted chalcones from phenones via conjugated nucleophilic substitution of propargylic alcohols

Phenones can be efficiently transformed into β-substituted chalcones in a two-step process. First, propargylic alcohols were obtained by addition of ethoxyacetylene anion to aromatic ketones. Activation of the propargylic alcohols using a catalytic amount

Alkoxyacetylenes from alkyl 1,2-dichlorovinyl ethers

Alkyl 1,2-dichlorovinyl ethers 4, prepared from sodium alkoxides 1 and trichloroethylene 2, react in tetrahydrofuran with two equivalents of butyllithium to afford lithium alkoxyacetylides 5. On the one hand, these acetylides react with ketones or dichlor