1422828-05-4

Basic information

• Product Name: C₂₃H₂₈IN₇O₃
• Synonyms: C₂₃H₂₈IN₇O₃
• CAS NO: 1422828-05-4
• Molecular Weight: 577.425
• Mol File: 1422828-05-4.mol

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₈IN₇O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₈IN₇O₃(1422828-05-4)
• EPA Substance Registry System: C₂₃H₂₈IN₇O₃(1422828-05-4)

Safety Data

• Hazardous Substances Data: 1422828-05-4(Hazardous Substances Data)

Upstream product

• 1422828-04-3 tert-butyl 3-iodo-1-(4-(methylamino)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylcarbamate 
• 1056149-69-9 (2E)-(N,N-dimethylamino)-2-butenoyl chloride 
• 151266-23-8 4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine 
• 350-46-9 4-Fluoronitrobenzene 
• 330793-99-2 3-iodo-1-(4-nitrophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
• 1422828-02-1 tert-butyl 3-iodo-1-(4-nitrophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylcarbamate 
• 1422828-03-2 tert-butyl 1-(4-aminophenyl)-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-ylcarbamate 

Downstream Products

• 1422828-06-5 (E)-N-(4-(4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenyl)-4-(dimethylamino)-N-methylbut-2-enamide 
• 1422827-13-1 (E)-N-(4-(4-amino-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenyl)-4-(dimethylamino)-N-methylbut-2-enamide 

Relevant articles and documents

Pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine compounds as kinase inhibitors

Disclosed herein are compounds of Formula (II) that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. Methods for the preparation of the compounds are disclosed. Also disclosed are pharmaceutical c