142292-45-3

Upstream product

• 1086234-95-8 2-Benzylidenamino-2-phenylaethanol 
• 153924-63-1 β-[(phenylmethylene)amino]-[R-(E)-]-benzeneethanol 

Downstream Products

• 142229-40-1 3-Methylene-5-phenyl-1-(1-phenyl-vinyl)-pyrrolidin-2-one 
• 142229-43-4 (R)-1-((R)-2-Hydroxy-1-phenyl-ethyl)-3-methylene-5-phenyl-pyrrolidin-2-one 
• 125216-88-8 (S)-3-methylene-5-phenyl-2-pyrrolidinone 
• 125216-87-7 α-methylene-γ-phenyl-γ-butyrolactam 
• 142292-48-6 (R)-1-((R)-2-Hydroxy-1-phenyl-ethyl)-3-methylene-5-phenyl-pyrrolidin-2-one 
• 142292-50-0 (R)-3-Methylene-5-phenyl-1-(1-phenyl-vinyl)-pyrrolidin-2-one 
• 125216-89-9 (-)-(R)-3-methylene-5-phenylpyrrolidin-2-one 

Relevant academic research and scientific papers

Sterecontrolled preparation of chiral secondary α-methylene γ-lactams by addition of organozinc reagents derived from 2-(bromomethyl)acrylates to imines using β-aminoalcohols as chiral auxiliaries.

Stereocontrolled addition of isolated organozinc reagents 1, prepared from 2-(bromomethyl)acrylates to imines, can be achieved with d.e. ca. 100percent using β-amino alcohols as chiral auxiliaries.High yields of pure R or S secondary α-methylene γ-lactams