1422959-03-2

Upstream product

• 181871-82-9 {(2R,3S)-3-[(tert-butyldimethylsilyl)oxy]-2,3-dihydrofuran-2-yl}methanol 
• 1233209-66-9 1β-(2,4-dichloropyrimidin-5-yl)-1,2-dideoxy-2,3-didehydro-3-O-(tert-butyldimethylsilyl)-D-ribofuranose 
• 1233209-67-0 1β-(2,4-dichloropyrimidin-5-yl)-1,2,3-trideoxy-3-oxo-D-ribofuranose 
• 1233209-68-1 1β-(2,4-dichloropyrimidin-5-yl)-1,2-dideoxy-D-ribofuranose 
• 1422959-02-1 1β-(2,4-dichloropyrimidin-5-yl)-1,2-dideoxy-5-O-(tert-butyl-dimethylsilyl)-D-ribofuranose 
• 55-21-0 benzamide 

Downstream Products

• 1422959-04-3 1β-[2,4-bis(benzoylamino)pyrimidin-5-yl]-1,2-dideoxy-D-ribofuranose 
• 1422959-05-4 1β-[2,4-bis(benzoylamino)pyrimidin-5-yl]-1,2-dideoxy-5-O-(4,4′-dimethoxytriphenylmethyl)-D-ribofuranose 
• 1422959-06-5 1β-[2,4-bis(benzoylamino)pyrimidin-5-yl]-1,2-dideoxy-5-O-(4,4’-dimethoxytriphenylmethyl)-D-ribofuranose-3-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite 

Relevant academic research and scientific papers

Genetic Code Expansion Facilitates Position-Selective Labeling of RNA for Biophysical Studies

Nature relies on reading and synthesizing the genetic code with high fidelity. Nucleic acid building blocks that are orthogonal to the canonical A-T and G-C base-pairs are therefore uniquely suitable to facilitate position-specific labeling of nucleic aci

Synthesis of 4-aminophthalimide and 2,4-diaminopyrimidine C-nucleosides as isosteric fluorescent DNA base substitutes

The 4-aminophthalimide C-nucleoside 1 was designed as an isosteric DNA base surrogate, and a synthetic route to nucleoside 1 together with the 2,4-diaminopyrimidine-C-nucleoside 2 as a potential counterbase was worked out. The key steps in both synthetic