(2R,3S)-3-[(tert-butyldimethylsilyl)oxy]-2,3-dihydrofuran-2-ylmethanol is a chiral dihydrofuran derivative featuring a tert-butyldimethylsilyl group and a hydroxyl group attached to the dihydrofuran ring. (2R,3S)-3-[(tert-butyldimethylsilyl)oxy]-2,3-dihydrofuran-2-ylmethanol is characterized by its specific stereochemistry, denoted by the (2R,3S) designation, and is widely utilized in organic synthesis.
181871-82-9
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Basic information
- Product Name: {(2R,3S)-3-[(tert-butyldimethylsilyl)oxy]-2,3-dihydrofuran-2-yl}methanol
- Synonyms: {(2R,3S)-3-[(tert-butyldimethylsilyl)oxy]-2,3-dihydrofuran-2-yl}methanol
- CAS NO:181871-82-9
- Molecular Formula:
- Molecular Weight: 230.379
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: {(2R,3S)-3-[(tert-butyldimethylsilyl)oxy]-2,3-dihydrofuran-2-yl}methanol(CAS DataBase Reference)
- NIST Chemistry Reference: {(2R,3S)-3-[(tert-butyldimethylsilyl)oxy]-2,3-dihydrofuran-2-yl}methanol(181871-82-9)
- EPA Substance Registry System: {(2R,3S)-3-[(tert-butyldimethylsilyl)oxy]-2,3-dihydrofuran-2-yl}methanol(181871-82-9)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 181871-82-9(Hazardous Substances Data)
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181871-82-9 Usage
Uses
Used in Pharmaceutical Synthesis:(2R,3S)-3-[(tert-butyldimethylsilyl)oxy]-2,3-dihydrofuran-2-ylmethanol is used as a versatile building block for the development of various pharmaceuticals. Its unique structure and stereochemistry allow for the creation of complex molecules with potential therapeutic applications.
Used in Agrochemical Production:
In the agrochemical industry, (2R,3S)-3-[(tert-butyldimethylsilyl)oxy]-2,3-dihydrofuran-2-ylmethanol is employed as a key intermediate for synthesizing biologically active molecules with pesticidal, herbicidal, or fungicidal properties.
Used in Organic Chemistry as a Protecting Group:
The tert-butyldimethylsilyl group in (2R,3S)-3-[(tert-butyldimethylsilyl)oxy]-2,3-dihydrofuran-2-ylmethanol serves as a protecting group for the hydroxyl functionality. It can be selectively removed under specific reaction conditions, making the compound an important intermediate for various organic synthesis processes.
Overall, (2R,3S)-3-[(tert-butyldimethylsilyl)oxy]-2,3-dihydrofuran-2-ylmethanol is a valuable compound in the fields of pharmaceuticals, agrochemicals, and organic chemistry, due to its unique structure, stereochemistry, and versatility as a building block and protecting group.
Check Digit Verification of cas no
The CAS Registry Mumber 181871-82-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,1,8,7 and 1 respectively; the second part has 2 digits, 8 and 2 respectively.Calculate Digit Verification of CAS Registry Number 181871-82:
(8*1)+(7*8)+(6*1)+(5*8)+(4*7)+(3*1)+(2*8)+(1*2)=159
159 % 10 = 9
So 181871-82-9 is a valid CAS Registry Number.
181871-82-9Upstream product
181871-82-9Downstream Products
- 950830-62-3 1β-(6-benzylpyridin-3-yl)-1,2-dideoxy-3,5-di-O-(t-butyldimethylsilyl)-D-ribofuranose
- 950830-63-4 1β-(6-phenylpyridin-3-yl)-1,2-dideoxy-3,5-di-O-(t-butyldimethylsilyl)-D-ribofuranose
- 1233209-82-9 1β-(2-phenyl-4-methylpyrimidin-5-yl)-1,2-dideoxy-3,5-di-O(t-butyldimethylsilyl)-D-ribofuranose
- 1233209-83-0 1β-(2-phenyl-4-methylpyrimidin-5-yl)-1,2-dideoxy-D-ribofuranose
- 1374985-56-4 3,5-di-O-(tert-butyldimethylsilyl)-1,2-dideoxy-1β-(2,4-diphenylpyrimidin-5-yl)-D-ribofuranose
- 1374985-57-5 1β-(2,4-diphenylpyrimidin-5-yl)-1,2-dideoxy-D-ribofuranose
- 1374985-70-2 1β-(4-amino-2-phenylpyrimidin-5-yl)-3,5-di-O-(tert-butyldimethylsilyl)-1,2-dideoxy-D-ribofuranose
- 1374985-72-4 3,5-di-O-(tert-butyldimethylsilyl)-1,2-dideoxy-1β-(4-methoxy-2-phenylpyrimidin-5-yl)-D-ribofuranose
- 1374985-84-8 3,5-di-O-(tert-butyldimethylsilyl)-1,2-dideoxy-1β-[4-(dimethylamino)-2-phenylpyrimidin-5-yl]-D-ribofuranose
- 1374985-71-3 1β-(4-amino-2-phenylpyrimidin-5-yl)-1,2-dideoxy-D-ribofuranose
- 1374985-73-5 1,2-dideoxy-1β-(4-methoxy-2-phenylpyrimidin-5-yl)-D-ribofuranose
- 1374985-74-6 1,2-dideoxy-1β-[4-(dimethylamino)-2-phenylpyrimidin-5-yl]-D-ribofuranose
- 1422958-90-4 1-(5-(N-(phenoxyacetyl)amino)phthalimid-3-yl)-1,2-dideoxy-β-D-ribofuranose
- 1422958-95-9 1-(5-(N-(phenoxyacetyl)amino)-N-(4,4'-dimethoxytrityl)phthalimid-3-yl)-5-O-(4,4'-dimethoxytrityl)-1,2-dideoxy-β-D-ribofuranose
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{(2R,3S)-3-[(tert-butyldimethylsilyl)oxy]-2,3-dihydrofuran-2-yl}methanol
