1422985-00-9Relevant academic research and scientific papers
The squaramide-catalyzed asymmetric Michael/cyclization tandem reaction for the synthesis of chiral trifluoromethylated hydroxyimino tetrahydrobenzofuranones
Liu, Wei,Lai, Xiaoyan,Zha, Gaofeng,Xu, Yan,Sun, Panpan,Xia, Tao,Shen, Yongcun
supporting information, p. 3603 - 3607 (2016/04/19)
An enantioselective synthesis of trifluoromethylated hydroxyimino tetrahydrobenzofuranones has been developed. 1,3-Dicarbonyl carbocyclic compounds react with β-CF3-β-disubstituted nitroalkenes in the presence of a chiral squaramide catalyst, p
Enantioselective Michael Addition of Pyrazolin-5-ones to β-CF3-β-Disubstituted Nitroalkenes Catalyzed by Squaramide Organocatalyst
Lai, Xiaoyan,Zha, Gaofeng,Liu, Wei,Xu, Yan,Sun, Panpan,Xia, Tao,Shen, Yongcun
supporting information, p. 1983 - 1988 (2016/08/09)
A highly enantioselective Michael addition of pyrazolin-5-ones with β-CF3-β-disubstituted nitroalkenes catalyzed by bifunctional squaramide has been developed. Various chiral β-CF3-β-5-hydroxy-pyrazolin-3-yl-disubstituted nitroalkane derivatives bearing all-carbon quaternary stereocenter were prepared in good yields (up to 88%) and excellent enantioselectivities (up to 97% ee).
Enantioselective organocatalytic reduction of β-trifluoromethyl nitroalkenes: An efficient strategy for the synthesis of chiral β-trifluoromethyl amines
Massolo, Elisabetta,Benaglia, Maurizio,Orlandi, Manuel,Rossi, Sergio,Celentano, Giuseppe
supporting information, p. 3589 - 3595 (2015/03/04)
An efficient organocatalytic stereoselective reduction of β-trifluoromethyl-substituted nitroalkenes, mediated by 3,5-dicarboxylic ester-dihydropyridines (Hantzsch ester type), has been successfully developed. A multifunctional thiourea-based (S)-valine d
Highly enantioselective construction of trifluoromethylated all-carbon quaternary stereocenters via nickel-catalyzed friedel-crafts alkylation reaction
Gao, Jian-Rong,Wu, Hao,Xiang, Bin,Yu, Wu-Bin,Han, Liang,Jia, Yi-Xia
supporting information, p. 2983 - 2986 (2013/04/10)
A highly enantioselective Friedel-Crafts alkylation reaction of indoles with β-CF3-β-disubstituted nitroalkenes was achieved using a Ni(ClO4)2-bisoxazoline complex as a catalyst, which afforded indole-bearing chiral compou
