1423012-51-4Relevant articles and documents
Synthesis and antifungal activity of some s-mercaptotriazolobenzothiazolyl amino acid derivatives
Aboelmagd,Ali, Ibrahim A.I.,Salem, Ezzeldin M.S.,Abdel-Razik
, p. 503 - 511 (2013/04/10)
A series of s-triazolobenzothiazolylthioacetyl/propionyl amino acid derivatives were synthesized with the aim of evaluating their antifungal activity. Their chemical structures were confirmed by 1H, 13C NMR, IR, mass spectrometry and elemental analyses. The synthesized derivatives were screened for their antifungal activity against Aspergillus flavus and Candida albicans. Five compounds (3, 5, 7c, 8 and 17) were found to possess high activity comparable to fluconazole at 100 μg/mL against C. albicans.