1423035-86-2

Upstream product

• 1423035-83-9 (1’S,3’S,7’R,8a’R)-7’-(methoxycarbonylmethyl)-5’-oxo-1-(phenylsulfonyl)spiro [indoline-3,1’-indolizidine]-3’-carboxylic acid 
• 1423035-84-0 (1’S,3’S,7’R,8a’R)-7’-(methoxycarbonylmethyl)-5’-oxo-1-(phenylsulfonyl)spiro[indoline-3,1’-indolizidine]-3’-carboselenoate 
• 1423035-82-8 (1’S,3’S,7’R,8a’R)-3’-(formyl)-7’-(methoxycarbonylmethyl)-5’-oxo-1-(phenylsulfonyl) spiro[indoline-3,1’-indolizidine] 
• 1423035-81-7 (1’S,3’S,7’R,8a’R)-3’-(hydroxymethyl)-7’-(methoxycarbonylmethyl)-5’-oxo-1-(phenyl-sulfonyl)spiro[indoline-3,1’-indolizidine] 
• 1423035-80-6 (3S,7R,8aS)-7-(methoxycarbonylmethyl)-5-oxo-3-[1-(phenylsulfonyl)-3-indolylmethyl]-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 
• 947509-90-2 (3S,7R,8aS)-3-(3-indolylmethyl)-7-(methoxycarbonylmethyl)-5-oxo-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 
• 430461-02-2 dimethyl 3-(2-oxoethyl)pentan-1,5-dioate 
• 154-09-6 L-tryptophanol 

Downstream Products

• 1423035-87-3 (1’S,7’S,8a’R)-7’-[2-(p-methoxybenzyloxy)ethyl]-5’-oxo-1-(phenylsulfonyl)spiro[indoline-3,1’-indolizidine] 
• 1423035-90-8 (1’S,6’S,7’S,8a’R)-6’-ethyl-7’-(2-hydroxyethyl)-5’-oxo-1-(phenylsulfonyl)spiro[indoline-3,1’-indolizidine] 
• 1423035-92-0 (1’S,6’S,7’S,8a’R)-6’-ethyl-7’-(methoxycarbonylmethyl)-5’-oxo-1-(phenylsulfonyl)spiro[indoline-3,1’-indolizidine] 
• 1423035-91-9 C₂₅H₂₈N₂O₅S 

Relevant academic research and scientific papers

Enantioselective formal synthesis of ent-rhynchophylline and ent-isorhynchophylline

Starting from (S)-tryptophanol, a formal synthesis of ent-rhynchophylline and ent-isorhynchophylline, involving stereoselective cyclocondensation, spirocyclization, and alkylation reactions, and the final adjustment of the oxidation level at the oxindole and piperidine moieties, is reported. The Royal Society of Chemistry 2013.