1423124-47-3Relevant academic research and scientific papers
A Metal–Organic Framework with Exceptional Activity for C?H Bond Amination
Wang, Le,Agnew, Douglas W.,Yu, Xiao,Figueroa, Joshua S.,Cohen, Seth M.
, p. 511 - 515 (2018/02/21)
The development of catalysts capable of fast, robust C?H bond amination under mild conditions is an unrealized goal despite substantial progress in the field of C?H activation in recent years. A Mn-based metal–organic framework (CPF-5) is described that promotes the direct amination of C?H bonds with exceptional activity. CPF-5 is capable of functionalizing C?H bonds in an intermolecular fashion with unrivaled catalytic stability producing >105 turnovers.
Enantioselective, intermolecular benzylic C-H amination catalysed by an engineered iron-haem enzyme
Prier, Christopher K.,Zhang, Ruijie K.,Buller, Andrew R.,Brinkmann-Chen, Sabine,Arnold, Frances H.
, p. 629 - 634 (2017/06/30)
C-H bonds are ubiquitous structural units of organic molecules. Although these bonds are generally considered to be chemically inert, the recent emergence of methods for C-H functionalization promises to transform the way synthetic chemistry is performed. The intermolecular amination of C-H bonds represents a particularly desirable and challenging transformation for which no efficient, highly selective, and renewable catalysts exist. Here we report the directed evolution of an iron-containing enzymatic catalyst - based on a cytochrome P450 monooxygenase - for the highly enantioselective intermolecular amination of benzylic C-H bonds. The biocatalyst is capable of up to 1,300 turnovers, exhibits excellent enantioselectivities, and provides access to valuable benzylic amines. Iron complexes are generally poor catalysts for C-H amination: in this catalyst, the enzyme's protein framework confers activity on an otherwise unreactive iron-haem cofactor.
Syntheses of a novel fluorinated trisphosphinoborate ligand and its copper and silver complexes. Catalytic activity toward nitrene transfer reactions
Arenas, Ismael,Fuentes, M. Angeles,Alvarez, Eleuterio,Diaz, Yolanda,Caballero, Ana,Castillon, Sergio,Perez, Pedro J.
, p. 3991 - 3999 (2014/05/06)
A novel fluorinated ligand, the anionic PhB(CH2P(p-CF 3C6H4)2)3 (PhBP 3 p-CF3Ph), has been synthesized and characterized, as well as its corresponding thallium, copper
Transition-metal-free benzylic C-H bond intermolecular amination utilizing chloramine-T and I2
Takeda, Youhei,Hayakawa, Junpei,Yano, Kazuki,Minakata, Satoshi
supporting information, p. 1672 - 1674 (2013/02/23)
An intermolecular benzylic C-H bond amination utilizing the combination of chloramine-T and I2 without the aid of transition-metal catalysts has been developed. The reaction was found applicable to a variety of benzene-substituted alkanes, as w
