142329-91-7Relevant academic research and scientific papers
Glycosylating reagent for the synthesis of linear and other α-L-fucosyl oligosaccharides
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, (2008/06/13)
A novel, efficient glycosylating reagent, R 3,4-O-isopropylidene-2-O-(4-methoxybenzyl)-1-thio-β -L-fucopyranoside wherein R is a lower alkyl or lower alkenyl of 1 to 8 carbons such as methyl or pentenyl, is described. This novel reagent provides for the facile synthesis of linear and other α-L-fucosyl oligosaccharides. In addition, a method for the preparation of 2'-O-α-L-fucopyranosyl-lactose, which comprises reacting the abovementioned glycosylating reagent with solvated 4-O-(6-O-acetyl-3,4-O-isopropylidene-β-D-galactopyranosyl)-2,3,5,6-di-O-isopropylidene-D-glucose, dimethyl acetal, a tetrabutylammonium halide and a catalyst and then de-O-acetylating the resulting reaction product with sodium methoxide methanol, is also disclosed.
A facile synthesis of nitrophenyl oligosaccharides containing the O-α-L-fucopyranosyl-(1 → 3)-2-acetamido-2-deoxy-β-D-glucopyranosyl unit at their nonreducing end
Jain,Piskorz,Matta
, p. 243 - 253 (2007/10/02)
A facile approach towards the synthesis of 4-nitrophenyl O-α-L-fucopyranosyl-(1 → 3)-2-acetamido-2-deoxy-β-D-glucopyranoside, 2-nitrophenyl O-α-L-fucopyranosyl-(1 → 3)-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-(1 → 6)-2-acetamido-2-deoxy-α-D-galactopyran
