142330-90-3

Upstream product

• 125849-94-7 3,5-dichloro-6-methyl-2(H)-1,4-oxazin-2-one 
• 108-88-3 toluene 

Downstream Products

• 143033-59-4 1-(5-Methoxy-4-p-tolyl-oxazol-2-yl)-ethanone 
• 143721-91-9 6-Chloro-1-methyl-4-p-tolyl-2-oxa-5-aza-bicyclo[2.2.2]oct-5-en-3-one 
• 142331-02-0 2-Chloro-3-methyl-4-phenyl-6-p-tolyl-pyridine 
• 142330-98-1 2-chloro-3-methyl-6-(methylphenyl)-5-phenylpyridine 
• 142330-97-0 methyl 6-chloro-5-methyl-2-(4-methylphenyl)-3-pyridinecarboxylate 
• 142331-01-9 2-Chloro-3-methyl-6-p-tolyl-isonicotinic acid methyl ester 

Relevant academic research and scientific papers

The synthesis of 3-functionalized 5-chloro-6-methyl-2H-1,4-oxazin-2-ones and of pyridines from cycloaddition-elimination reactions with substituted acetylenic compounds

Selective functionalisation of the chlorimine group in 3,5-dichloro-6-methyl-2H-1,4-oxazin-2-one is usually realised in appropriate conditions, by electrophilic catalysis avoiding reaction of the lactone function. The azadiene system in the 3-substituted

Functionalisation in position 3 of 3,5-dichloro-2H-1,4-oxazin-2-ones

Electrophilic catalysis is shown to give selective substitution of the imidoyl chloride group in 3,5-dichloro-2H-1,4-oxazin-2-ones, avoiding competitive reactions of the nucleophile with the lactone function.With other nucleophiles (SCN-, CHsu