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Usage

Uses

Used in Chemical Synthesis:
2,4-Hexadienoic acid, 6-oxo-, methyl ester, (2Z,4E)is used as an intermediate in the synthesis of (2E,4E,6Z)-2,4,6-Decatrienoic Acid Methyl Ester (~80%) (D210650). This application is significant because it contributes to the production of a specific chemical compound that may have various applications in different industries.
In the Chemical Industry:
2,4-Hexadienoic acid, 6-oxo-, methyl ester, (2Z,4E)is used as a key component in the synthesis of various chemical products. Its role in the production of (2E,4E,6Z)-2,4,6-Decatrienoic Acid Methyl Ester highlights its importance in the development of new compounds with potential applications in various sectors, such as pharmaceuticals, materials science, and agriculture.

Upstream product

• 6214-23-9 methyl (2Z)-3-iodoprop-2-enoate 
• 107-02-8 acrolein 
• 6932-46-3 (2Z,4E)-hexadienoic acid methyl ester 
• 53892-48-1 (2Z,4Z)-hexadienoic acid methyl ester 

Relevant academic research and scientific papers

Chloroperoxidase-catalyzed oxidation of conjugated dienoic esters

The chloroperoxidase (CPO)-catalyzed oxidations of dienes conjugated to an ester group were studied using tert-butyl hydroperoxide as the terminal oxidant.

Asymmetric acetate aldol reactions in connection with an enantioselective total synthesis of macrolactin A

Asymmetric aldol-like reactions of cinnamaldehyde, dienal 3 (fragment C7-C12 of macrolactin A), and dienal 4 (fragment C15-C24) with (i) chiral acetylthiazolidinethione-derived enolates, (ii) chiral boron enolates, and (iii) silyl enolates in the presence of chiral titanium-2,2'-dinaphthol complexes are compared. Use of the thiazolidinethiode auxiliary and TiCl4 shows practical advantages; e.g., C5-C12 fragment 7 has been isolated enantiomerically pure in 74% yield. Copyright (C) 1996 Elsevier Science Ltd.

A CONVENIENT STEREOSELECTIVE SYNTHESIS OF CONJUGATED (2Z)-EN-4-YNOIC AND (2Z,4Z)- AND (2Z,4E)-DIENOIC ACID DERIVATIVES FROM PROPIOLIC ACID DERIVATIVES

The palladium-catalysed one-pot sequential reaction of propiolic acid derivatives with lithium halides first, and then with terminal alkynes or alkenes affords conjugated (2Z)-en-4-ynoic and (2Z,4Z)- and (2Z,4E)-dienoic acid derivatives with high stereoselectivity.