14235-78-0

Basic information

• Product Name: 4,4'-Methylenebispyrocatechol
• Synonyms: 4,4'-Methylenebis(1,2-benzenediol);4,4'-Methylenebispyrocatechol
• CAS NO: 14235-78-0
• Molecular Formula: C₁₃H₁₂O₄
• Molecular Weight: 0
• Mol File: 14235-78-0.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4,4'-Methylenebispyrocatechol(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-Methylenebispyrocatechol(14235-78-0)
• EPA Substance Registry System: 4,4'-Methylenebispyrocatechol(14235-78-0)

Safety Data

• Hazardous Substances Data: 14235-78-0(Hazardous Substances Data)

Upstream product

• 620-92-8 bis-(4-hydroxyphenyl)methane 
• 93-07-2 Veratric acid 
• 4131-03-7 bis(3,4-dimethoxyphenyl)methanone 
• 91-16-7 1,2-dimethoxybenzene 
• 65487-76-5 2,2′,3,3′-tetrabromo-4,4′,5,5′-tetrahydroxydiphenylmethane 
• 4971-68-0 bis(3,4-methylenedioxyphenyl)methane 
• 50-00-0 formaldehyd 
• 120-80-9 benzene-1,2-diol 
• 1158-27-6 bis(3,4-dimethoxyphenyl)methane 

Downstream Products

• 1130428-40-8 2,2',3-trichloro-4,4',5,5'-tetrahydroxydiphenylmethane 
• 1130428-42-0 2,2',3,3'-tetrachloro-4,4',5,5'-tetrahydroxydiphenylmethane 
• 1130428-36-2 2-chloro-3',4,4',5-tetrahydroxydiphenylmethane 
• 167634-40-4 2,2'-dichloro-4,4',5,5'-tetrahydroxydiphenylmethane 
• 1158-27-6 bis(3,4-dimethoxyphenyl)methane 
• 41634-67-7 bis-(2-bromo-4,5-dimethoxy-phenyl)-methane 

Relevant articles and documents

Photochemistry of bisphenol F in aqueous solutions: A mechanistic study

In the present work aqueous photochemistry of bisphenol F has been studied by means of stationary (282 nm) and laser flash photolysis (266 nm). Photoionization with formation of hydrated electron - phenoxyl radical pair was observed to be the main primary photochemical process (φmono = 2 × 10-2). Phenoxyl radical decays in recombination and reaction with superoxide anion radical formed during scavenging of hydrated electron by dissolved oxygen. The quantum yield of BPF photodegradation was evaluated to be 2 × 10-3 upon 282 nm exposure. The main primary product of BPF photolysis determined by LC-MS is hydroxylated BPF.

Inhibition of human carbonic anhydrase isozymes I, II and VI with a series of bisphenol, methoxy and bromophenol compounds

Carbonic anhydrase inhibitors (CAI) are valuable molecules as they have several therapeutic applications, including anti-glaucoma activity. In this study, inhibition of three human carbonic anhydrase (hCA, EC 4.2.1.1) isozymes I, II and VI with a series o

Synthesis and antimicrobial activities of halogenated bis(hydroxyphenyl)methanes

A series of halophenols was prepared by the reaction of bis(hydroxyphenyl)methanes with effective halogenating agents such as bromine and sulfuryl chloride. One of these compounds, a biologically active halophenol-2,2′,3,3′-tetrabromo-4,4′,5,5′-tetrahydroxydiphenylmethane (1)-frequently isolated from red algae, was synthesized for the first time. Other halophenols included several novel compounds, together with known derivatives that were synthesized from the phenolic intermediates, bis(3,4-dihydroxyphenyl)methane (5) and bis(2-hydroxyphenyl)methane (14). All of the synthesized compounds were tested for antimicrobial activity against Gram-positive, Gram-negative bacteria and fungi. The preliminary structure-activity relationship was investigated in order to determine the essential structural requirements for their antimicrobial activity. Of all these halophenols, 2,2′,3,3′,6-pentabromo-4,4′,5,5′-tetrahydroxydiphenylmethane (8) was found to be the most active against Candida albicans, Aspergillus fumigatus, Trichophyton rubrum, and Trichophyton mentagrophytes while 3,3′,5,5′-tetrachloro-2,2′-dihydroxydiphenylmethane (18) exerted a powerful antibacterial effect against Staphylococcus aureus, Bacillus subtilis, Micrococcus luteus, Proteus vulgaris, and Salmonella typhimurium.