1423783-89-4

Basic information

• Product Name: {2-hydroxy-5-[7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1,6-dienyl]phenyl}-N,N,N-trimethylmethanaminium iodide
• Synonyms: {2-hydroxy-5-[7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1,6-dienyl]phenyl}-N,N,N-trimethylmethanaminium iodide
• CAS NO: 1423783-89-4
• Molecular Weight: 537.395
• Mol File: 1423783-89-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {2-hydroxy-5-[7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1,6-dienyl]phenyl}-N,N,N-trimethylmethanaminium iodide(CAS DataBase Reference)
• NIST Chemistry Reference: {2-hydroxy-5-[7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1,6-dienyl]phenyl}-N,N,N-trimethylmethanaminium iodide(1423783-89-4)
• EPA Substance Registry System: {2-hydroxy-5-[7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1,6-dienyl]phenyl}-N,N,N-trimethylmethanaminium iodide(1423783-89-4)

Safety Data

• Hazardous Substances Data: 1423783-89-4(Hazardous Substances Data)

Upstream product

• 74-88-4 methyl iodide 
• 116546-04-4 3-<(dimethylamino)methyl>-4-hydroxybenzaldehyde 
• 123-08-0 4-hydroxy-benzaldehyde 

Relevant articles and documents

Design and synthesis of dimethylaminomethyl-substituted curcumin derivatives/analogues: Potent antitumor and antioxidant activity, improved stability and aqueous solubility compared with curcumin

A series of dimethylaminomethyl-substituted curcumin derivatives/analogues were designed and synthesized. All compounds effectively inhibited HepG2, SGC-7901, A549 and HCT-116 tumor cell lines proliferation in MTT assay. Particularly, compounds 2a and 3d showed much better activity than curcumin against all of the four tumor cell lines. Antioxidant test revealed that these compounds had higher free radical scavenging activity than curcumin towards both DPPH and galvinoxyl radicals. Furthermore, the aqueous solubility and stability of the target compounds were also significantly improved compared with curcumin.