142387-23-3

Upstream product

• 30516-87-1 3'-azido-2',3'-deoxythymidine 
• 603-35-0 triphenylphosphine 

Downstream Products

• 142387-25-5 3'-deoxy-3'-isocyanato-thymidine 
• 142387-24-4 3'-(<(4-methylphenyl)iminocarbonyl>imino)-3'-deoxythymidine 
• 142387-30-2 1-[(2R,4S,5S)-5-Hydroxymethyl-4-(5-phenylamino-tetrazol-1-yl)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 142387-32-4 1-[(2R,4S,5S)-5-Hydroxymethyl-4-(5-p-tolylamino-tetrazol-1-yl)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 142387-31-3 1-{(2R,4S,5S)-4-[5-(4-Chloro-phenylamino)-tetrazol-1-yl]-5-hydroxymethyl-tetrahydro-furan-2-yl}-5-methyl-1H-pyrimidine-2,4-dione 
• 142387-33-5 1-{(2R,4S,5S)-4-[5-(4-Ethoxy-phenylamino)-tetrazol-1-yl]-5-hydroxymethyl-tetrahydro-furan-2-yl}-5-methyl-1H-pyrimidine-2,4-dione 

Relevant academic research and scientific papers

Microwave-assisted synthesis of dinucleoside analogues containing a thiazolidin-4-one linkage via one-pot tandem Staudinger/aza-Wittig/cyclization

Dinucleosides containing a thiazolidin-4-one linkage were prepared by one-pot tandem Staudinger/aza-Wittig/intermolecular cyclization under microwave irradiation and their structures were confirmed. Preliminary examination of HIV-RT inhibition showed that

Synthesis of 3'-(5-amino-1,2,3,4-tetrazol-1-yl)-3'-deoxythymidines

A one-pot synthesis of the new 3'-(5-amino-1,2,3,4-tetrazol-1-yl)-3,-deoxythymidines from 3,-Azido-3'-deoxythymidine (AZT) is described. The key step is the 1,3-dipolar cycloaddition of hydrazoic acid to intermediate carbodiimides.