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CAS

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1424-06-2

(17alpha)-pregna-1,4-diene-3,20-dione, also known as 17α-Pregna-1,4-diene-3,20-dione or 17α-Pregnadiene-3,20-dione, is a synthetic steroid hormone and a derivative of progesterone. It is structurally similar to the hormone cortisol and possesses anti-inflammatory and immunosuppressive properties.

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  • 1424-06-2 Structure

  • Basic information

    1. Product Name: (17alpha)-pregna-1,4-diene-3,20-dione
    2. Synonyms:
    3. CAS NO:1424-06-2
    4. Molecular Formula: C21H28O2
    5. Molecular Weight: 312.4458
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1424-06-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 449.2°C at 760 mmHg
    3. Flash Point: 167.4°C
    4. Appearance: N/A
    5. Density: 1.1g/cm3
    6. Vapor Pressure: 2.91E-08mmHg at 25°C
    7. Refractive Index: 1.556
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: (17alpha)-pregna-1,4-diene-3,20-dione(CAS DataBase Reference)
    11. NIST Chemistry Reference: (17alpha)-pregna-1,4-diene-3,20-dione(1424-06-2)
    12. EPA Substance Registry System: (17alpha)-pregna-1,4-diene-3,20-dione(1424-06-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1424-06-2(Hazardous Substances Data)

1424-06-2 Usage

Uses

Used in Pharmaceutical Industry:
(17alpha)-pregna-1,4-diene-3,20-dione is used as an intermediate in the production of steroid medications, such as hydrocortisone, due to its structural similarity to cortisol and its anti-inflammatory and immunosuppressive properties.
Used in Medical Treatments:
(17alpha)-pregna-1,4-diene-3,20-dione is used as a therapeutic agent for the treatment of various medical conditions, including allergies, asthma, arthritis, and certain skin disorders, owing to its anti-inflammatory and immunosuppressive properties.
Used in Veterinary Medicine:
(17alpha)-pregna-1,4-diene-3,20-dione is used as a medication for the treatment of inflammation and pain in animals, taking advantage of its anti-inflammatory and immunosuppressive properties to alleviate symptoms and improve the well-being of animals.

Check Digit Verification of cas no

The CAS Registry Mumber 1424-06-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,2 and 4 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1424-06:
(6*1)+(5*4)+(4*2)+(3*4)+(2*0)+(1*6)=52
52 % 10 = 2
So 1424-06-2 is a valid CAS Registry Number.

1424-06-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name (8S,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one

1.2 Other means of identification

Product number -
Other names 1.4-Pregnadien-3,20-dion

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1424-06-2 SDS

1424-06-2Downstream Products

1424-06-2Relevant articles and documents

Direct Formation of the Steroid Nucleus by a Biomimetic Cyclization

Johnson, William S.,McCarry, Brian E.,Markezich, R. L.,Boots, Sharon G.

, p. 352 - 359 (2007/10/02)

The aim of this study was to synthesize the trienynol 3 and to study its cyclization.The substrate was synthesized by a convergent route, the key step being the stereoselective Wittig-Schlosser condensation of the known aldehyde 19 with the phosphorane 18

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