142467-27-4

Upstream product

• 17299-34-2 3-ethylcyclohex-2-en-1-one 
• 504-02-9 1,3-cylohexanedione 
• 5323-87-5 3-Ethoxycyclohex-2-en-1-one 

Downstream Products

• 912959-46-7 (+/-)-1-ethyl-2-cyclohexene-1-propanol acetate 
• 844655-73-8 4-[3-(acetyloxy)propyl]-4-ethyl-2-cyclohexen-1-one 
• 844655-74-9 4-[3-(acetyloxy)propyl]-4-ethyl-2-iodo-2-cyclohexen-1-one 
• 912959-47-8 4-ethyl-4-(3-hydroxypropyl)-2-(2-nitrophenyl)-2-cyclohexen-1-one 
• 844655-78-3 4-(3-azidopropyl)-4-ethyl-2-(2-nitrophenyl)-2-cyclohexen-1-one 
• 844655-76-1 4-[3-(acetyloxy)propyl]-4-ethyl-2-(2-nitrophenyl)-2-cyclohexen-1-one 
• 912959-48-9 4-ethyl-4-(3-hydroxypropyl)-2-(2-nitrophenyl)-2-cyclohexen-1-one methanesulfonate 
• 912959-31-0 (+/-)-1-ethyl-2-cyclohexene-1-propanamine 
• 912959-30-9 (+/-)-3-(3-azidopropyl)-3-ethyl-1-cyclohexene 
• 912959-22-9 (+/-)-1-ethyl-2-cyclohexene-1-ethanol acetate 
• 912959-23-0 (+/-)-4-[2-(acetyloxy)ethyl]-4-ethyl-2-cyclohexen-1-one 
• 912959-29-6 (+/-)-1-ethyl-2-cyclohexene-1-propanol methanesulfonate 
• 912959-21-8 (+/-)-4-[2-(acetyloxy)ethyl]-4-ethyl-2-iodo-2-cyclohexen-1-one 
• 912959-32-1 [3-(1-ethyl-cyclohex-2-enyl)-propyl]-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

SUBSTITUTED FLUOROETHYL UREAS AS ALPHA 2 ADRENERGIC AGENTS

Therapeutic compounds, and methods, compositions, and medicaments related thereto are disclosed herein.

Tandem radical cyclization reactions, initiated at nitrogen, as an approach to the CDE-tricylic cores of certain post-secodine alkaloids

-The nitrogen-radical precursors (10-15) have been prepared and subjected to reaction conditions expected to promote tandem radical cyclization sequences leading to the CDE-tricyclic frameworks associated with alkaloids such as vindoline (1) and ibophylli

Exploiting the palladium[0]-catalysed Ullmann cross-coupling reaction in natural products chemistry: Application to a total synthesis of the alkaloid (±)-aspidospermidine

The application of Ullmann cross-coupling reaction for the synthesis of the alkaloid (±)-aspidospermidine was studied. The initial step associated with the second stage of the synthesis of aspidospermidine involved the Pd[0]-catalyzed Ullmann cross-coupli

Application of the palladium(0)-catalyzed ullmann cross-coupling reaction in a total synthesis of (±)-aspidospermidine and thus representing an approach to the lower hemisphere of the binary indole-indoline alkaloid vinblastine

As part of ongoing studies directed towards the construction of the anti-cancer agent vinblastine (1), the related but structurally less complex natural product aspidospermidine (3) has been synthesized. Two approaches to target 3 were pursued. In the fir

(2-hydroxy)ethyl-thioureas useful as modulators of alpha2B adrenergic receptors

Compounds of formula (i) and of formula (ii) wherein the symbols have the meaning disclosed in the specification, specifically or selectively modulate α2B and/or α2C adrenergic receptors in preference over α2A adrenergic receptors, and as such are useful for alleviating chronic pain and allodynia and have no or only minimal cardivascular and/or sedatory activity.

Chemo-enzymatic preparation of optically active endo- bicyclo[4.1.0]heptan-2-ols

Resolutions of endo-bicyclo[4.1.O]heptan-2-ols were achieved by acylation in the presence of lipase from Candida antarctica (Novozym). The (1S,2R,6R) enantiomers reacted faster and the enantiomeric ratios were between 60 and 800 for the 6-substituted bicycloalkanols.

Lipase-mediated Resolution of 2-Cyclohexen-1-ols as Chiral Building Blocks en route to Eburnane Alkaloids

Lipase catalyzed esterification of several 2-cyclohexen-1-ols proceeds with excellent enantioselectivity leading to (S)-enantiomers as promising chiral building blocks en route to eburnane alkaloids.

Oxidation by Cobalt(III) Acetate. Part 7. Regioselective Synthesis of Substituted Cyclohexenyl Acetates

The oxidation of alkylcyclohexenes with cobalt(III) acetate has been studied in acetic acid under nitrogen. 1-Alkylcyclohexenes gave exclusively the corresponding 3-acetoxy-1-alkylcyclohexenes in good yields.Similarly, 3- and 4-methylcyclohexene afforded 3-acetoxy-6- and -5-methylcyclohexene, respectively, in suprising high selectivities.In all cases, the position α to the alkyl group was completely or largely insensitive to CoIII.The results can be explained in terms of steric hindrance of the alkyl group which limits the attack of CoIII at a hindered site.