142467-27-4Relevant articles and documents
SUBSTITUTED FLUOROETHYL UREAS AS ALPHA 2 ADRENERGIC AGENTS
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Page/Page column 44, (2008/12/04)
Therapeutic compounds, and methods, compositions, and medicaments related thereto are disclosed herein.
Exploiting the palladium[0]-catalysed Ullmann cross-coupling reaction in natural products chemistry: Application to a total synthesis of the alkaloid (±)-aspidospermidine
Banwell, Martin G.,Lupton, David W.
, p. 213 - 215 (2007/10/03)
The application of Ullmann cross-coupling reaction for the synthesis of the alkaloid (±)-aspidospermidine was studied. The initial step associated with the second stage of the synthesis of aspidospermidine involved the Pd[0]-catalyzed Ullmann cross-coupli
(2-hydroxy)ethyl-thioureas useful as modulators of alpha2B adrenergic receptors
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, (2008/06/13)
Compounds of formula (i) and of formula (ii) wherein the symbols have the meaning disclosed in the specification, specifically or selectively modulate α2B and/or α2C adrenergic receptors in preference over α2A adrenergic receptors, and as such are useful for alleviating chronic pain and allodynia and have no or only minimal cardivascular and/or sedatory activity.