143839-99-0Relevant academic research and scientific papers
Regio- And Stereoselective Addition of HO/OOH to Allylic Alcohols
Wang, Xiao-Tao,Han, Wei-Bo,Chen, Hui-Jun,Zha, Qinghong,Wu, Yikang
, p. 10007 - 10021 (2020/08/28)
A range of allylic alcohols are shown to readily react with ethereal H2O2 in the presence of catalytic amounts of Na2MoO4-gly or MoO2(acac)2, affording the C═C trans hydroxylation-hydroperoxylation products in good yields with high regio- and stereoselect
Indole alkaloids. A combined chemical and enzymatic route for eburnane ring construction: Formal synthesis of (-)-eburnamonine
Palmisano, Giovanni,D'Anniballe, Paolo,Santagostino, Marco
, p. 9487 - 9494 (2007/10/02)
A stereocontrolled formal synthesis of (-)-eburnamonine 1, a tetracyclic indole alkaloid used as antihypertensive drug, has been achieved through the use of [3.3]-sigmatropic rearrangement (Claisen rearrangement) of the enantiopure β-alkoxy acrylate 4, av
A Novel Synthesis Including Asymmetric Synthesis of α,β-Unsaturated γ-Hydroxy Carbonyl Compounds from Enones with Carbon Homologation
Satoh, Tsuyoshi,Motohashi, Shigeyasu,Tokutake, Norio,Yamakawa, Koji
, p. 2966 - 2973 (2007/10/02)
Reaction of the carbanion derived from 1-chloroalkyl aryl sulfoxides with enones gave 1,2-adducts in good yields.Treatment of the adduct with potassium benzenethiolate afforded α-phenylthio β,γ-unsaturated carbonyl compound through an α,β-epoxy sulfoxide.
Lipase-mediated Resolution of 2-Cyclohexen-1-ols as Chiral Building Blocks en route to Eburnane Alkaloids
Carrea, Giacomo,Danieli, Bruno,Palmisano, Giovanni,Riva, Sergio,Santagostino, Marco
, p. 775 - 784 (2007/10/02)
Lipase catalyzed esterification of several 2-cyclohexen-1-ols proceeds with excellent enantioselectivity leading to (S)-enantiomers as promising chiral building blocks en route to eburnane alkaloids.
