142504-40-3Relevant academic research and scientific papers
Direct and Regioselective Di-α-fucosylation on the Secondary Rim of β-Cyclodextrin
Verkhnyatskaya, Stella A.,de Vries, Alex H.,Douma-de Vries, Elmatine,Sneep, Renze J. L.,Walvoort, Marthe T. C.
supporting information, p. 6722 - 6727 (2019/03/26)
A straightforward glycosylation method is described to regio- and stereoselectively introduce two α-l-fucose moieties directly to the secondary rim of β-cyclodextrin. Using NMR and MS fragmentation studies, the nonasaccharide structure was determined, which was also visualized using molecular dynamics simulations. The reported glycosylation method proved to be robust on gram-scale, and may be generally applied to directly glycosylate β-cyclodextrins to make well-defined multivalent glycoclusters.
Channel-Type Molecular Structures Part 2 Synthesis of Bouquet-Shaped Molecules Based on a β-Cyclodextrin Core
Canceill, Josette,Jullien, Ludovic,Lacombe, Liliane,Lehn, Jean-Marie
, p. 791 - 812 (2007/10/02)
A new series of channel-type molecules presenting the features of potential transmembrane structures is described.They result from the grafting of amphiphilic side chains on a β-cyclodextrin derivative 3 that constitutes the organizing core.They belong to the 'bouquet' family (B).Compounds bearing poly(oxyethylene) side chains, BOCD 16 and 17, and their polymethylene analogues BCCD 18 and 19, were synthesized.The properties investigated emphasize the suitability of such molecules to be incorporated into lipid bilayer membranes.
