1425508-91-3

Upstream product

• 1822-73-7 phenylthioethylene 
• 3805-10-5 2,2-(dimethyl)-2-phenylacetaldehyde 
• 1513-65-1 2,6-difluoro pyridine 
• 1425509-17-6 4-methyl-4-phenyl-2-(phenylthio)pent-1-en-3-ol 

Downstream Products

• 1425508-90-2 2-fluoro-6-((4-methyl-4-phenyl-2-(phenylsulfonyl)pent-1-en-3-yl)oxy)pyridine 
• 1425508-59-3 7-((6-fluoropyridin-2-yl)oxy)-4,4-dimethyl-6-(phenylsulfonyl)hept-6-en-2-one 
• 1425508-58-2 7-((6-fluoropyridin-2-yl)oxy)-4,4-dimethyl-6-(phenylsulfonyl)hept-6-en-2-one 
• 1425508-54-8 (E)-4,4,8-trimethyl-8-phenyl-6-(phenylthio)non-6-en-2-one 
• 1425508-55-9 (Z)-4,4,8-trimethyl-8-phenyl-6-(phenylthio)non-6-en-2-one 

Relevant academic research and scientific papers

From a remarkable manifestation of polar effects in a radical fragmentation to the convergent synthesis of highly functionalized ketones

A new radical addition/C-C bond fragmentation process is reported. Vinyl carbinols derived from 2-methyl-2-phenylpropanal react with radicals generated from xanthates to give the corresponding ketones. The radical cleavage reaction proceeds under mild conditions, in good to high yield, and in the presence of the unprotected carbinol. Highly functionalized 1,5-diketones and pyridines are readily available using this approach.

Tri- and tetrasubstituted functionalized vinyl sulfides by radical allylation

2-Fluoropyridinyl-6-oxy- precursors derived from phenyl vinyl sulfide react with radicals generated from xanthates via an addition-elimination process to furnish the corresponding vinyl sulfides in good yields. This convergent method is operationally simp