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4,6-Dihydroxy-5-formylpyrimidine, also known as pyrimidine-5-aldehyde, is a pyrimidine derivative with the molecular formula C5H4N2O3. It features two hydroxyl groups and one formyl group attached to the pyrimidine ring. This chemical compound plays a pivotal role as a key intermediate in the biosynthesis of thiamine (vitamin B1) across various organisms, such as plants and microorganisms. Its involvement in the metabolism of thiamine and its potential therapeutic applications make it a significant compound in the pharmaceutical and agrochemical industries.

14256-99-6

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14256-99-6 Usage

Uses

Used in Pharmaceutical Industry:
4,6-Dihydroxy-5-formylpyrimidine is used as an intermediate in the synthesis of various pharmaceuticals. Its role in the production of thiamine and related compounds contributes to the development of treatments for thiamine deficiency and associated disorders. 4,6-Dihydroxy-5-formylpyrimidine's potential therapeutic applications extend to the enhancement of health and well-being by addressing vitamin deficiencies.
Used in Agrochemical Industry:
In the agrochemical sector, 4,6-Dihydroxy-5-formylpyrimidine serves as a precursor in the synthesis of certain agrochemicals. Its use in this industry aids in the development of products that can improve crop yields and protect plants from diseases, thereby contributing to sustainable agriculture and food security.
Used in Vitamin B1 Biosynthesis:
4,6-Dihydroxy-5-formylpyrimidine is utilized as a key intermediate in the biosynthesis of thiamine (vitamin B1) in organisms. This application is crucial for maintaining the metabolic processes that rely on thiamine, ensuring the proper functioning of biological systems in plants and microorganisms.
Used in Research and Development:
4,6-Dihydroxy-5-formylpyrimidine is also used in research and development settings to study the biochemical processes related to thiamine metabolism. Understanding the role of 4,6-Dihydroxy-5-formylpyrimidine in these processes can lead to advancements in the fields of biochemistry and medicine, potentially uncovering new therapeutic targets and applications.

Check Digit Verification of cas no

The CAS Registry Mumber 14256-99-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,2,5 and 6 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 14256-99:
(7*1)+(6*4)+(5*2)+(4*5)+(3*6)+(2*9)+(1*9)=106
106 % 10 = 6
So 14256-99-6 is a valid CAS Registry Number.

14256-99-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 4,6-Dihydroxy-5-formylpyrimidine

1.2 Other means of identification

Product number -
Other names 1,4-Dihydro-6-hydroxy-4-oxo-5-pyrimidinecarboxaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:14256-99-6 SDS

14256-99-6Relevant academic research and scientific papers

Method for synthesizing 4,6-dichloropyrimidine-5-carbonitrile

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Paragraph 0051; 0052; 0063-0065, (2018/07/07)

The invention relates to a method for synthesizing a compound 4,6-dichloropyrimidine-5-carbonitrile. The method has the advantages of mild reaction conditions, environmental protection, easiness in preservation of an intermediate, and convenience for large-scale production.

Studies of Azoles and Azines. CI. Reaction of 4,6-Dihydroxypyrimidine and Barbituric Acid with 4,6-Dihydroxypyrimidine-5-carbaldehyde

Moskvin,Petrova,Ivin

, p. 1703 - 1706 (2007/10/03)

Reaction of barbituric acid with 4,6-dihydroxypyrimidine-5-carbaldehyde in water at 20-60°C yields 5-(4,6-dihydroxypyrimidin-5-ylmethylene)barbituric acid. The same reaction performed in acetic acid at 120°C yields 5-aminomethylenebarbituric acid. One of the pyrimidine rings also opens in the reaction of 4,6-dihydroxypyrimidine with 4,6-dihydroxypyrimidine-5-carbaldehyde, which yields pyrano[2,3-d]pyrimidine-6-carboxamide derivatives.

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