142569-70-8 Usage
Description
2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol is a complex organic compound characterized by its pale-yellow foam appearance. It is a derivative of the pharmaceutical compound montelukast, which is primarily used for treating asthma and allergic rhinitis. This specific compound is identified as an impurity in the synthesis or formulation of montelukast.
Uses
Used in Pharmaceutical Industry:
2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol is used as an impurity in the production of montelukast for the pharmaceutical industry. As an impurity, it is essential to monitor and control its presence to ensure the safety, efficacy, and quality of the final drug product. The compound may also be of interest for research purposes, potentially leading to the development of new therapeutic agents or a better understanding of the parent compound's mechanisms of action.
Chemical Properties:
The chemical properties of 2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol include its pale-yellow foam appearance, which may be indicative of its physical state and stability under certain conditions. Further research into its chemical behavior, reactivity, and potential interactions with other compounds could provide valuable insights for its application in the pharmaceutical industry and other related fields.
Check Digit Verification of cas no
The CAS Registry Mumber 142569-70-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,5,6 and 9 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 142569-70:
(8*1)+(7*4)+(6*2)+(5*5)+(4*6)+(3*9)+(2*7)+(1*0)=138
138 % 10 = 8
So 142569-70-8 is a valid CAS Registry Number.
InChI:InChI=1/C29H28ClNO2/c1-29(2,33)26-9-4-3-7-21(26)13-17-28(32)23-8-5-6-20(18-23)10-15-25-16-12-22-11-14-24(30)19-27(22)31-25/h3-12,14-16,18-19,28,32-33H,13,17H2,1-2H3/b15-10+/t28-/m0/s1
142569-70-8Relevant articles and documents
PROCESS FOR THE PURIFICATION OF OPTICALLY IMPURE 2-(2-(3(S)-(3-(7-CHLORO-2-QUINOLINYL)ETHENYL)PHENYL)-3-HYDROXY-PROPYL)PHENYL-2-PROPANOL
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Page/Page column 7, (2009/01/20)
A process for purifying an optically impure 2-(2-(3(S)-(3-(7-chloro-2-quinolinyl)- ethenyl)-phenyl)-3-(hydroxylpropyl)phenyl)-2 propanol is disclosed. The purified compound typically has an enantiomeric excess higher than 99%, and can be used to prepare montelukast and salts thereof.
Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists
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, (2008/06/13)
Compounds having the formula I: STR1 are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.