14257-79-5

Basic information

• Product Name: b-D-Galactopyranose,2-amino-2-deoxy-, hydrochloride (9CI)
• Synonyms: Galactopyranose,2-amino-2-deoxy-, hydrochloride, b-D- (8CI); 2-Amino-2-deoxy-b-D-galactopyranose hydrochloride; NSC 283301
• CAS NO: 14257-79-5
• Molecular Formula: C₆H₁₃NO₅*ClH
• Molecular Weight: 179.1711
• Mol File: 14257-79-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 449.9°Cat760mmHg
• Flash Point: 225.9°C
• Density: 1.563g/cm³
• CAS DataBase Reference: b-D-Galactopyranose,2-amino-2-deoxy-, hydrochloride (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: b-D-Galactopyranose,2-amino-2-deoxy-, hydrochloride (9CI)(14257-79-5)
• EPA Substance Registry System: b-D-Galactopyranose,2-amino-2-deoxy-, hydrochloride (9CI)(14257-79-5)

Safety Data

• Hazardous Substances Data: 14257-79-5(Hazardous Substances Data)

Upstream product

• 103782-08-7 allosamidin 
• 41847-61-4 (3S,4S,5R)-2-(hydroxymethyl)tetrahydropyran-2,3,4,5-tetrol 
• 887472-18-6 N-benzyl-D-tagatosylamine 

Downstream Products

• 66395-17-3 1-methyl-1-nitroso-3-(2-deoxy-D-mannos-2-yl)urea 
• 66395-17-3 1-methyl-1-nitroso-3-(2-deoxy-D-galactos-2-yl)urea 
• 149038-33-5 (4S,5S)-4-(D-arabino-tetritol-1-yl)-1-(4-chlorophenyl)-5-hydroxyimidazolidin-2-one 
• 3006-58-4 2-<(benzyloxycarbonyl)amino>-2-deoxy-D-mannopyranose 
• 653600-56-7 1,3,4,6-tetra-O-acetyl-2-azidoacetylamido-2-deoxy-α,β-D-mannopyranose 
• 14086-92-1 1,3,4,6-tetra-O-acetyl-2-benzamido-2-deoxy-β-D-mannopyranose 
• 14086-92-1 1,3,4,6-tetra-O-acetyl-2-benzamido-2-deoxy-α-D-mannopyranose 
• 1355005-40-1 (3R,4R,5R,6R)-6-(acetoxymethyl)-3-aminotetrahydro-2H-pyran-2,4,5-triyl triacetate hydrochloride 
• 100483-05-4 2-deoxy-2-[[(phenylmethoxy)carbonyl]amino]-D-galactopyranose-1,3,4,6-tetraacetate 
• 29086-03-1 N-Bromacetyl-D-galactopyranosylamin 
• 198200-67-8 phenyl 3,4,6-tri-O-acetyl-2-deoxy-1-thio-2-trichloroacetamido-β-D-galactopyranoside 
• 148968-89-2 2-azido-3,4,6-tri-O-benzyl-2-deoxy-D-mannopyranose 
• 765308-76-7 p-methylphenyl 3,4,6-tri-O-benzyl-2-deoxy-2-azido-1-thio-D-mannopyranoside 
• 765308-75-6 p-methylphenyl 2-deoxy-2-azido-3,4,6-tri-O-acetyl-1-thio-D-mannopyranoside 

Relevant articles and documents

Synthesis of N-protected galactosamine building blocks from D-tagatose via the heyns rearrangement

N-Acetyl-D-galactosamine (11), a very important naturally occurring building block of oligosaccharides, is easily accessible via the Heyns rearrangement of D-tagatose (3) with benzylamine. The short and efficient synthesis of various differently N-protected D-galactosamine derivatives is reported. Copyright Taylor & Francis Group, LLC.

Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals

O-acetylated glycals react with ceric ammonium nitrate in the presence of sodium azide to provide, in good yield, O-acetylated 2-azido-2-deoxy glycosyl nitrates. These nitrates can be used to prepare 2-amino-2-deoxy sugars, such as D-galactosamine and lactosamine. The O-acetylated 2-azido-2-deoxy glycosyl nitrates can alternately be converted to O-acetylated 2-azido-2-deoxy glycosyl halides which are useful in the preparation of O-acetylated 2-azido-2-deoxy glycosides, which in turn can be reduced to 2-amino-2-deoxy glycosides. Of particular interest are the syntheses of 2-amino-2-deoxy glycosides which correspond to the terminal units of the antigenic determinant for the human A blood group. Attachment of these glycosides to a solid support provides immunoabsorbents which efficiently and preferentially absorb anti-A antibodies from blood plasma.