Cas 1425925-83-2,2-[(1R,2S)-5-chloro-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-1H-isoindole-1,3(2H)-dione

1425925-83-2

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Basic information

Product Name: 2-[(1R,2S)-5-chloro-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-1H-isoindole-1,3(2H)-dione
Synonyms: 2-[(1R,2S)-5-chloro-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-1H-isoindole-1,3(2H)-dione
CAS NO:1425925-83-2
Molecular Formula:
Molecular Weight: 313.74
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 2-[(1R,2S)-5-chloro-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-1H-isoindole-1,3(2H)-dione(CAS DataBase Reference)
NIST Chemistry Reference: 2-[(1R,2S)-5-chloro-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-1H-isoindole-1,3(2H)-dione(1425925-83-2)
EPA Substance Registry System: 2-[(1R,2S)-5-chloro-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-1H-isoindole-1,3(2H)-dione(1425925-83-2)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1425925-83-2(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1425925-83-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,5,9,2 and 5 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1425925-83:
(9*1)+(8*4)+(7*2)+(6*5)+(5*9)+(4*2)+(3*5)+(2*8)+(1*3)=172
172 % 10 = 2
So 1425925-83-2 is a valid CAS Registry Number.

1425925-83-2Upstream product

1425925-83-2Downstream Products

1425925-85-4 (1R,2S)-5-chloro-2-methoxyindan-1-amine

1425925-83-2Relevant academic research and scientific papers

INHIBITORS OF NEDD8-ACTIVATING ENZYME

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Paragraph 055; 056; 0109; 0110, (2013/03/26)

Disclosed are chemical entities which are inhibitors of Nedd8-activating enzyme (NAE), namely, the compound {(1S,2S,4R)-4-[(6-{[(1R,2S)-5-chloro-2-methoxy-2,3-dihydro-1H-inden-1-yl]amino}pyrimidin-4-yl)oxy]-2-hydroxycyciopentyl}methyl sulfamate and pharmaceutically acceptable salts thereof; solid state forms thereof; and prodrugs thereof. Also disclosed are methods of using the chemical entities to treat disorders such as cancer.

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