1425937-41-2

Upstream product

• 1425937-43-4 (1R,2R,3R)-3-(3-(benzyloxy)benzyl)-2-((3S,1E)-3-hydroxyoct-1-enyl)-4-methylenecyclopentanol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 91842-31-8 (1E)-tributyl-stannyl-(3S)-tert-butyldimethylsilyloxyoctene 
• 1425937-39-8 (2R,3R,4R)-2-(3-(benzyloxy)benzyl)-4-triethylsilyloxy-3-((3S,1E)-3-triethylsilyloxyoct-1-enyl)cyclopentanone 
• 1425937-59-2 (3R)-1-[3-(benzyloxy)benzyl]-5-oxo-3-(triethylsilyloxy)cyclopent-1-ene 
• 183073-00-9 (1S,2E)-1-pentyl-3-(1,1,1-tributylstannyl)-2-propenyl (1,1,1-triethylsilyl) ether 
• 1425937-38-7 (2R,3R,4R)-2-(3-(benzyloxy)benzyl)-4-tert-butyldimethylsilyloxy-3-((3S,1E)-3-tert-butyldimethylsilyloxyoct-1-enyl)cyclopentanone 
• 74-95-3 1,1-dibromomethane 

Downstream Products

• 1425937-62-7 (1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-(tert-butyldimethylsilyloxy)-1-((3S,1E)-3-(tert-butyl dimethylsilyloxy)oct-1-enyl)-1H-cyclopenta[b]naphthalen-5-yl benzoate 
• 1425937-55-8 (1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-((3S,1E)-3-hydroxyoct-1-enyl)-1H-cyclopenta[b]naphthalen-5-yl benzoate 
• 1425937-56-9 (1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-((S)-3-hydroxyoctyl)-1H-cyclopenta[b]naphthalen-5-yl benzoate 
• 101692-02-8 (1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-1-((S)-3-hydroxyoctyl)-1H-cyclopenta[b]naphthalene-2,5-diol 
• 81846-19-7 treprostinil 
• 1425937-50-3 ((1S,2S,3R,4R)-2-(3-hydroxybenzyl)-4-(tert-butyldimethylsilyloxy)-3-((3S,1E)-3-(tert-butyldimethylsilyloxy)oct-1-enyl)cyclopentyl)methyl 4-methylbenzenesulfonate 
• 1425937-44-5 ((1S,2S,3R,4R)-2-(3-(benzyloxy)benzyl)-4-(tert-butyldimethylsilyloxy)-3-((3S,1E)-3-(tert-butyldimethylsilyloxy)oct-1-enyl)cyclopentyl)methanol 
• 1425937-46-7 ((1S,2S,3R,4R)-2-(3-(benzyloxy)benzyl)-4-(tert-butyldimethylsilyloxy)-3-((3S,1E)-3-(tert-butyldimethylsilyloxy)oct-1-enyl)cyclopentyl)methyl methanesulfonate 
• 1425937-47-8 ((1S,2S,3R,4R)-2-(3-(benzyloxy)benzyl)-4-(tert-butyldimethylsilyloxy)-3-((3S,1E)-3-(tert-butyldimethylsilyloxy)oct-1-enyl)cyclopentyl)methyl 4-methylbenzenesulfonate 
• 1425937-49-0 ((1S,2S,3R,4R)-2-(3-hydroxybenzyl)-4-(tert-butyldimethylsilyloxy)-3-((3S,1E)-3-(tert-butyldimethylsilyloxy)oct-1-enyl)cyclopentyl)methyl methanesulfonate 
• 1425937-51-4 ((1S,2S,3R,4R)-2-(3-hydroxybenzyl)-4-(tert-butyldimethylsilyloxy)-3-((S)-3-(tert-butyldimethylsilyloxy)octyl)cyclopentyl)methyl 4-methylbenzenesulfonate 

Relevant academic research and scientific papers

INTERMEDIATES FOR THE SYNTHESIS OF BENZINDENE PROSTAGLANDINS AND PREPARATIONS THEREOF

Novel processes for preparing optically active cyclopentanones 1 which are useful for the preparation of benzindene Prostaglandins and novel cyclopentanones are provided. The invention also provides novel processes of preparing benzindene Prostaglandins and novel intermediates for benzindene Prostaglandins.

Intermediates for the synthesis of benzindene prostaglandins and preparations thereof

Novel processes for preparing optically active cyclopentanones 1 which are useful for the preparation of benzindene Prostaglandins and novel cyclopentanones are provided. The invention also provides novel processes of preparing benzindene Prostaglandins and novel intermediates for benzindene Prostaglandins.