1425974-12-4

Basic information

• Product Name: C₃₁H₂₈N₄O₂S
• Synonyms: C₃₁H₂₈N₄O₂S
• CAS NO: 1425974-12-4
• Molecular Weight: 520.655
• Mol File: 1425974-12-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₁H₂₈N₄O₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₁H₂₈N₄O₂S(1425974-12-4)
• EPA Substance Registry System: C₃₁H₂₈N₄O₂S(1425974-12-4)

Safety Data

• Hazardous Substances Data: 1425974-12-4(Hazardous Substances Data)

Upstream product

• 138608-95-4 2-(benzylthio)-4-(4-methoxyphenyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile 
• 25519-80-6 4-(benzoyl)piperidine hydrochloride 
• 70638-54-9 5-cyano-4-oxo-6-(4-methoxyphenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine 
• 123-11-5 4-methoxy-benzaldehyde 

Relevant articles and documents

Synthesis of a 2,4,6-trisubstituted 5-cyano-pyrimidine library and evaluation of its immunosuppressive activity in a Mixed Lymphocyte Reaction assay

A series of novel pyrimidine analogues were synthesized and evaluated for immunosuppressive activity in the Mixed Lymphocyte Reaction assay, which is well-known as the in vitro model for in vivo rejection after organ transplantation. Systematic variation of the substituents at positions 2, 4 and 6 of the pyrimidine scaffold led to the discovery of 2-benzylthio-5-cyano-6-(4- methoxyphenyl)-4-morpholinopyrimidine with an IC50 value of 1.6 μM in the MLR assay.