1426080-01-4

Upstream product

• 504-29-0 2-aminopyridine 
• 79-24-3 Nitroethane 
• 874-42-0 2,4-dichlorobenzaldeyhde 
• 52287-58-8 (E)-2,4-dichloro-1-(2-nitroprop-1-en-1-yl)benzene 

Relevant academic research and scientific papers

Polyethylene gylcol (PEG-400) as an efficient and recyclable reaction medium for one-pot three-component synthesis of imidazo[1,2-a]pyridine derivatives

Polyethylene glycol (PEG) was found to be an inexpensive nontoxic and effective medium for the one-pot three-component synthesis of imidazo[1,2-a]pyridine derivatives under catalyst-free conditions in excellent yields. Environmental acceptability, low cost, high yields and recyclability of the polyethylene glycol are the important features of this protocol.

Iron(III)-catalyzed denitration reaction: One-pot three-component synthesis of imidazo[1,2-a]pyridine derivatives

An iron(III)-catalyzed one-pot three-component cross-coupling nitration reaction of 2-aminopyridines, aldehydes and nitroalkanes, straightforwardly forms imidazo[1,2-a]pyridine derivatives and is described in this report. The system shows good functional-group tolerance and proceeds smoothly in moderate to good yields. An iron(III)-catalyzed one-pot three-component cross-coupling nitration reaction of 2-aminopyridines, aldehydes, and nitroalkane, leading to the straightforward formation of imidazo[1,2-a]pyridine derivatives has been reported. In this procedure, the starting materials are commercially available. The system shows good functional-group tolerance and proceeds smoothly in moderate to good yields. Copyright

Iron(II)-catalyzed denitration reaction: Synthesis of 3-methyl-2- arylimidazo[1,2-a]pyridine derivatives from aminopyridines and 2-methylnitroolefins

A variety of ways to synthesize imidazo[1,2-a]pyridines have been reported and many approaches are devoted to the functionalization of imidazo[1,2-a] pyridines. However, the use of a denitration reaction in the synthesis of imidazo[1,2-a]pyridines has not