14261-92-8Relevant academic research and scientific papers
SMALL MOLECULE INHIBITORS OF APOBEC3G AND APOBEC3B
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, (2015/07/23)
The present invention is directed to compositions and methods for inhibition of APOBEC-related DNA cytosine deaminase enzymes, and to methods of using the compounds for treatment of a disease in a patient, such as an infectious disease or a cancer. The in
Cycloaddition of furfurylamines to maleic anhydride and its substituted derivatives
Zaytsev,Mikhailova,Airiyan,Galkina,Golubev,Nikitina,Zubkov,Varlamov
, p. 505 - 513 (2012/10/29)
The regio- and stereoselectivity of the [4+2] cycloaddition of maleic, citraconic, dichloromaleic, and dibromomaleic anhydrides to difurfuryl amines and secondary furfurylamines were studied. N-Furfuryl-, N-phenyl-, and N-benzylhexahydrooxoepoxyisoindole-7-carboxylic acids were synthesized. An approach was developed for obtaining hexahydroepoxyoxoisoindole-7-carboxylic acid unsubstituted at the nitrogen atom. Aromatization of the oxabicycloheptene fragment of the dihaloepoxyiso-indolonecarboxylic acids gave a series of 7-carboxy-2-R-isoindol-1-ones.
Preparative synthesis of 7-carboxy-2-R-isoindol-1-ones
Varlamov,Boltukhina,Zubkov,Sidorenko,Chernyshev,Grudinin
, p. 22 - 28 (2007/10/03)
A preparative method for the synthesis of 7-carboxy-2-R-isoindol-1-ones was developed on the basis of the [4+2] cycloaddition of secondary furfurylamines to maleic anhydride.
