1426165-15-2Relevant articles and documents
Optimized S-trityl-l-cysteine-based inhibitors of kinesin spindle protein with potent in vivo antitumor activity in lung cancer xenograft models
Good, James A. D.,Wang, Fang,Rath, Oliver,Kaan, Hung Yi Kristal,Talapatra, Sandeep K.,Podgórski, Dawid,MacKay, Simon P.,Kozielski, Frank
supporting information, p. 1878 - 1893 (2013/05/08)
The mitotic kinesin Eg5 is critical for the assembly of the mitotic spindle and is a promising chemotherapy target. Previously, we identified S-trityl-l-cysteine as a selective inhibitor of Eg5 and developed triphenylbutanamine analogues with improved pot
