1426175-70-3

Upstream product

• 23660-00-6 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-2,4-dihydroxybenzaldehyde 
• 74-88-4 methyl iodide 
• 95-01-2 2,4-Dihydroxybenzaldehyde 
• 6138-90-5 trans-geranyl bromide 
• 59384-87-1 (E)-2-(3,7-dimethylocta-2,6-dienyloxy)-4-methoxybenzaldehyde 
• 673-22-3 2-Hydroxy-4-methoxybenzaldehyde 

Downstream Products

• 1426175-72-5 C₂₈H₃₉NO₃ 
• 1381789-18-9 (E)-5-(3,7-dimethylocta-2,6-dien-1-yl)-6-methoxy-4-(methoxymethoxy)-2-phenethylisoindolin-1-one 
• 1360446-87-2 (E)-5-(3,7-dimethylocta-2,6-dienyl)-6-methoxy-4-(methoxy-methoxy)-2-phenethylisoindolin-1-one 
• 79295-49-1 5-(7-(3,7-dimethylocta-2,6-dien-1-yl)-6-methoxybenzofuran-2-yl)benzene-1,3-diol 
• 1426175-75-8 C₂₀H₂₈O₄ 

Relevant academic research and scientific papers

An efficient total synthesis of mulberrofuran B and L

An efficient approach has been developed for the synthesis of mulberrofuran B and L from 2,4-dihydroxybenzaldehyde and 5-bromoresorcinol. The key steps of the synthesis are neutral Al2O3-mediated regioselective geranylation, Ramirez gem-dibromoolefination, and the Suzuki coupling.

Concise total synthesis of hericerin natural product

A concise total synthesis of hericerin, a natural product, is described. The all-synthetic sequence comprises five steps and was accomplished in 34% overall yield starting from commercially available 2-hydroxy-4- methoxybenzaldehyde. The key steps were the introduction of the geranyl group using a ether-phenol rearrangement and the formation of isoindolinone through a Pd(OAc)2-catalyzed carbonylative ring closure.