59384-87-1

Upstream product

• 673-22-3 2-Hydroxy-4-methoxybenzaldehyde 
• 6138-90-5 trans-geranyl bromide 

Downstream Products

• 1426175-75-8 C₂₀H₂₈O₄ 
• 1426175-70-3 (E)-3-(3,7-dimethylocta-2,6-dienyl)-2-hydroxy-4-methoxybenzaldehyde 
• 1426175-72-5 C₂₈H₃₉NO₃ 
• 1381789-18-9 (E)-5-(3,7-dimethylocta-2,6-dien-1-yl)-6-methoxy-4-(methoxymethoxy)-2-phenethylisoindolin-1-one 
• 1360446-87-2 (E)-5-(3,7-dimethylocta-2,6-dienyl)-6-methoxy-4-(methoxy-methoxy)-2-phenethylisoindolin-1-one 

Relevant academic research and scientific papers

Concise total synthesis of hericerin natural product

A concise total synthesis of hericerin, a natural product, is described. The all-synthetic sequence comprises five steps and was accomplished in 34% overall yield starting from commercially available 2-hydroxy-4- methoxybenzaldehyde. The key steps were the introduction of the geranyl group using a ether-phenol rearrangement and the formation of isoindolinone through a Pd(OAc)2-catalyzed carbonylative ring closure.