1426249-33-3Relevant academic research and scientific papers
TBAI-catalyzed synthesis of α-ketoamides via sp3 C-H radical/radical cross-coupling and domino aerobic oxidation
Fan, Weizheng,Shi, Dongyang,Feng, Bainian
, p. 4638 - 4641 (2015/07/02)
A TBAI-catalyzed one-pot synthesis of α-ketoamides via sp3 C-H radical/radical cross-coupling and domino aerobic oxidation was developed. This synthesis is suitable for abroad range of substrates. The control experiments suggested a possible oxidative coupling mechanism.
Cu(ii)-catalyzed decarboxylative acylation of acyl C-H of formamides with α-oxocarboxylic acids leading to α-ketoamides
Li, Dengke,Wang, Min,Liu, Jie,Zhao, Qiong,Wang, Lei
supporting information, p. 3640 - 3642 (2013/05/21)
CuBr2-catalyzed decarboxylative acylation of the acyl C-H of N-monosubstituted and N,N-disubstituted formamides with α-oxocarboxylic acids leading to α-ketoamides was developed, which generated the corresponding products in good yields. The Royal Society of Chemistry 2013.
Direct use of formamides as amino group sources via C-N bond cleavage: A catalytic oxidative synthesis of α-ketoamides from acetophenones and formamides under metal-free conditions
Zhao, Qiong,Miao, Tao,Zhang, Xiaobin,Zhou, Wei,Wang, Lei
, p. 1867 - 1873 (2013/04/10)
An efficient and direct use of formamides as amino group sources for the synthesis of α-ketoamides was developed under metal-free conditions. The reaction was based on the oxidative coupling of acetophenones with formamides and generated the desired products in good yields in the presence of t-BuOOH/I2/PhCO2H.
