1426258-77-6Relevant academic research and scientific papers
Regioselective decarboxylative cross-coupling of carboxy isoquinoline N -oxides
Rouchet, Jean-Baptiste E. Y.,Schneider, Cédric,Fruit, Corinne,Hoarau, Christophe
, p. 5919 - 5927 (2015/06/16)
A straightforward method for direct decarboxylative arylation of 1- and 3-carboxy isoquinaldic acid N-oxides with aryl iodides is reported. The reaction proceeded selectively at the carboxy function site to exclusively give the corresponding C-1/sub
Efficient synthesis of isoquinoline derivatives via AgOTf/Cu(OTf) 2-cocatalyzed cyclization of 2-alkynyl benzaldoxime
Zhao, Xiaona,Fan, Weidong,Miao, Zhiwei,Chen, Ruyu
, p. 1714 - 1720 (2013/05/21)
An efficient, AgOTf and Cu(OTf)2 multicatalytic intramolecular cycloisomerization of 2-alkynylbenzaldoxime is reported. Isoquinoline N-oxides have been found to be deoxygenated to the corresponding quinolines in good yields in dimethylformamide/ dichloroethane (v/v 5:1) as solvent at 120 °C. Copyright Taylor & Francis Group, LLC.
Generation of 1-aroxyisoquinolines via a silver-catalyzed reaction of 2-alkynylbenzaldoxime with phenol in the presence of p-toluenesulfonyl chloride
Xiao, Qing,Zheng, Danqing,Ding, Qiuping,Wu, Jie
supporting information, p. 5119 - 5122 (2013/06/27)
A silver-catalyzed reaction of 2-alkynylbenzaldoxime with phenol promoted by p-toluenesulfonyl chloride leads to 1-aroxyisoquinolines in good yields. The presence of p-toluenesulfonyl chloride as an activator is essential for the successful transformation
AgOTf-catalyzed one-pot reactions of 2-alkynylbenzaldoximes with α,β-unsaturated carbonyl compounds
Ding, Qiuping,Wang, Dan,Luo, Puying,Liu, Meiling,Pu, Shouzhi,Zhou, Liyun
supporting information, p. 1949 - 1956 (2013/10/22)
AgOTf-catalyzed one-pot reactions of 2-alkynylbenzaldoximes with various α,β-unsaturated carbonyl compounds under mild conditions are described, which provides a facile and efficient pathway for the synthesis of 1-alkylated isoquinoline derivatives. The m
One-pot two-step synthesis of 1-position arylated 1,3-disubstituted isoquinoline N-oxides
Ding, Qiuping,Wang, Dan,Sang, Xiaoyan,Lin, Yuqing,Peng, Yiyuan
supporting information, p. 8869 - 8874 (2012/10/29)
A one-pot two-step reaction of 2-alkynylbenzaldoximes with aryl halides has been developed, which offers the 1-position arylated 1,3-disubstituted isoquinoline N-oxides in moderate to good yields in most cases. The isoquinoline N-oxide intermediate was pr
