1426260-73-2

Basic information

• Product Name: 2-(2,4-dichlorophenethyl)-8-(2,4-dimethoxyphenyl)-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol
• Synonyms: 2-(2,4-dichlorophenethyl)-8-(2,4-dimethoxyphenyl)-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol
• CAS NO: 1426260-73-2
• Molecular Weight: 488.411
• Mol File: 1426260-73-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(2,4-dichlorophenethyl)-8-(2,4-dimethoxyphenyl)-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,4-dichlorophenethyl)-8-(2,4-dimethoxyphenyl)-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol(1426260-73-2)
• EPA Substance Registry System: 2-(2,4-dichlorophenethyl)-8-(2,4-dimethoxyphenyl)-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol(1426260-73-2)

Safety Data

• Hazardous Substances Data: 1426260-73-2(Hazardous Substances Data)

Upstream product

• 1426260-53-8 2-(2,4-dichlorophenethyl)-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol 
• 151-10-0 1,3-Dimethoxybenzene 
• 4602-73-7 3,4-dihydro-7-hydroxy-6-methoxy-isoquinoline 
• 108649-59-8 1-(2-bromoethyl)-2,4-dichlorobenzene 

Relevant articles and documents

8-PHENYL-ISOQUINOLINES AND PHARMACEUTICAL COMPOSITION THEREOF USED IN THE TREATMENT OF IRRITABLE BOWEL SYNDROME

A series of 8-phenyl-isoquinoline derivatives (I) exhibit high binding affinity to 5-HT7 receptor (5-HT7R) and demonstrate potent antinociceptive activity in two animal models for Irritable Bowel Syndrome (IBS) by intraperitoneal injection (i.p.) or by oral administration (p.o.). These 5-HT7 receptor antagonists are a new class of therapeutic agents for the treatment of IBS.