1426313-97-4Relevant academic research and scientific papers
A novel approach to the synthesis of α-aminonitriles using triphenyl-phosphine dibromide under solvent-free conditions
Chaturvedi, Devdutt,Chaturvedi, Amit K.,Dwivedi, Parmesh K.,Mishra, Nisha
, p. 33 - 36 (2013)
A quick and highly efficient, one-pot, three-component, solvent-free method for the synthesis of α-aminonitriles starting from the corresponding carbonyl compounds, amines, and trimethylisocyanide using triphenylphosphine dibromide, has been developed. Diverse α-aminonitriles have been synthesized in good to excellent yields (80-99%) using a range of aldehydes, ketones and amines. Georg Thieme Verlag Stuttgart · New York.
