1426319-05-2Relevant academic research and scientific papers
Enantioselective oxidative functionalization of the Csp3-H bond adjacent to a nitrogen atom for rapid access to β-hydroxyl-α-amino acid derivatives
Qiu, Lin,Guo, Xin,Qian, Yu,Jing, Changcheng,Ma, Chaoqun,Liu, Shunying,Hu, Wenhao
supporting information, p. 11831 - 11833 (2016/10/09)
Highly chemoselective and enantioselective one-pot reactions involved in the oxidative functionalization of Csp3-H bonds adjacent to nitrogen atoms in N-aryl glycine esters were developed. The method provided rapid access to a variety of highly functionalized β-hydroxyl-α-amino acid derivatives from simple starting materials under mild conditions.
A highly enantioselective four-component reaction for the efficient construction of chiral β-hydroxy-α-amino acid derivatives
Qian, Yu,Jing, Changcheng,Liu, Shunying,Hu, Wenhao
supporting information, p. 2700 - 2702 (2013/05/08)
An enantioselective four-component reaction of a diazoketone, water, an aniline and ethyl glyoxylate in the presence of catalytic Rh2(OAc) 4 and a chiral Br?nsted acid was developed to efficiently produce β-hydroxy-α-amino acid derivatives in good yields with high diastereoselectivity and enantioselectivity. The Royal Society of Chemistry 2013.
