1426409-59-7

Upstream product

• 3156-41-0 1-nitro-4-(2-nitrovinyl)benzene 
• 108-59-8 malonic acid dimethyl ester 
• 18731-47-0 1-(4-nitrophenyl)-2-nitroethanol 
• 555-16-8 4-nitrobenzaldehdye 
• 3156-41-0 1-nitro-4-[(E)-2-nitroeth-1-enyl]benzene 
• 75-52-5 nitromethane 

Relevant academic research and scientific papers

Efficient and productive asymmetric Michael addition: Development of a highly enantioselective quinidine-based organocatalyst for homogeneous recycling via nanofiltration

The relatively high cost and low availability of chiral organocatalysts, in addition to the high catalytic loading required (typically 1-30 mol%), pose a general challenge to the industrial development of economical asymmetric organocatalytic processes. T

Solvent free enantioselective catalysis with chiral cobalt(iii) Werner complexes via ball milling

Enantioselective additions of malonate esters to nitroalkenes can be catalyzed by a variety of salts of chiral cobalt(iii) trications [Co(1,2-diamine)3]3+ in the presence of nitrogen donor bases in acetone. Catalysts that feature enantiopure 1,2-diphenyle

Chiral Cobalt(III) Tris(1,2-diamine) Catalysts That Incorporate Nitrogenous Base Containing Anions for the Bifunctional Activation of Nucleophiles and Electrophiles in Enantioselective Addition Reactions

The lipophilic diastereomeric cobalt complexes Λ or Δ-[Co((S,S)-dpen)3]3+2Cl-BArf-(Λ or Δ-(S,S)-2 3+2Cl-BArf-; dpen/BArf-= 1,2-dipheny

Mimicking Enzymes: Asymmetric Induction inside a Carbamate-Based Steroidal Cleft

Cholic acid has been elaborated into a carbamate-based tripodal architecture, which is able to promote an asymmetric organic transformation inside its chiral cavity. The nature of this steroidal catalyst has been disclosed by quantum-chemical calculations. It comprises the preorganization and confinement of the reagents within the cavity of the steroid to form a supramolecular complex held together by means of cooperative H-bond contacts. This operational mode resembles that of some enzymes.

Cinchona alkaloid-based chiral catalysts act as highly efficient multifunctional organocatalysts for the asymmetric conjugate addition of malonates to nitroolefins

New pentaerythritol tetrabromide-based chiral quaternary ammonium salts acting as organocatalysts (7a and 7b) have been prepared and used as organocatalysts for enantioselective Michael addition reactions between various nitroolefins and Michael donors (malonates) under mild reaction conditions, such as lower concentration of base and catalyst and room temperature, with very good chemical yields (up to 97%) and ee's (up to 99%).

In situ preparation of a multifunctional chiral hybrid organic-inorganic catalyst for asymmetric multicomponent reactions

A chiral mesoporous organosilica material incorporating a urea based-cinchona derivative and propylamine groups was prepared by a co-condensation method. The multisite solid catalyst efficiently promoted the asymmetric multicomponent reaction of aldehydes, malonates and nitromethane.