1426415-58-8

Basic information

• Product Name: 2,7-bis(4-(trifluoromethyl)phenyl)-1,8-naphthyridine
• Synonyms: 2,7-bis(4-(trifluoromethyl)phenyl)-1,8-naphthyridine
• CAS NO: 1426415-58-8
• Molecular Weight: 418.341
• Mol File: 1426415-58-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,7-bis(4-(trifluoromethyl)phenyl)-1,8-naphthyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,7-bis(4-(trifluoromethyl)phenyl)-1,8-naphthyridine(1426415-58-8)
• EPA Substance Registry System: 2,7-bis(4-(trifluoromethyl)phenyl)-1,8-naphthyridine(1426415-58-8)

Safety Data

• Hazardous Substances Data: 1426415-58-8(Hazardous Substances Data)

Upstream product

• 141-86-6 2.6-diaminopyridine 
• 128796-39-4 4-trifluoromethylphenylboronic acid 
• 55243-02-2 2,7-dichloro-1,8-naphthyridine 

Relevant articles and documents

Ruthenium-Catalyzed Enantioselective Hydrogenation of 1,8-Naphthyridine Derivatives

The first asymmetric hydrogenation of 2,7-disubstituted 1,8-naphthyridines catalyzed by chiral cationic ruthenium diamine complexes has been developed. A wide range of 1,8-naphthyridine derivatives were effectively hydrogenated to give 1,2,3,4-tetrahydro-1,8-naphthyridines with up to 99% ee and full conversions. The method provides a practical and facile approach to the preparation of valuable chiral heterocyclic building blocks and useful motifs for a new kind of P,N-ligand.

Suzuki-miyaura reactions of 2,7-dichloro-1,8-naphthyridine

2,7-Diaryl- and 2,7-dialkenyl-1,8-naphthyridines were prepared in high yields by Suzuki-Miyaura reactions of 2,7-dichloro-1,8-naphthyridines. While most of the products proved to be not or only weakly fluorescent, we observed a strong fluorescence in case of 2,7-bis(4-methoxyphenyl)-1,8-naphthyridine containing two electron-donating aryl groups. Georg Thieme Verlag Stuttgart - New York.