1426429-81-3Relevant articles and documents
Facile synthesis of α-methylidene-γ-butyrolactones: Intramolecular Rauhut-Currier reaction promoted by chiral acid-base organocatalysts
Takizawa, Shinobu,Nguyen, Tue Minh-Nhat,Grossmann, André,Suzuki, Michitaka,Enders, Dieter,Sasai, Hiroaki
, p. 1202 - 1209 (2013/02/23)
The acid-base organocatalyzed intramolecular Rauhut-Currier (RC) reaction of the dienone enolates has been developed. The enantioselective RC process produces the highly functionalized α-methylidene-γ-butyrolactones as a single diastereomer with up to 98% ee.