1426533-86-9

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 579-74-8 2-Methoxyacetophenone 
• 872057-29-9 3-(4-chlorophenyl)-1-(2-methoxyphenyl)-2-propen-1-one 
• 1426534-27-1 C₂₂H₁₉ClN₂O 
• 1426534-12-4 C₂₂H₁₇ClN₂O 
• 38372-01-9 2-(5-(4-chlorophenyl)-1-phenyl-1H-pyrazol-3-yl)phenol 

Relevant academic research and scientific papers

Structure-guided design, synthesis and in vitro evaluation of a series of pyrazole-based fatty acid binding protein (FABP) 3 ligands

We designed a series of pyrazole-based carboxylic acids as candidate ligands of heart fatty acid binding protein (H-FABP, or FABP3), based on a comparison of the X-ray crystallographic structures of adipocyte fatty acid binding protein (FABP4)-selective inhibitor (BMS309403) complex and FABP3-elaidic acid complex. Some of the synthesized compounds exhibited dual FABP3/4 ligand activity, and some exhibited selectivity for FABP3.